Lipase-catalyzed synthesis of red pitaya ( Hylocereus polyrhizus ) seed oil esters for cosmeceutical applications: process optimization using response surface methodology.

Autor:	Abdullah A; Department of Chemistry, Faculty of Science, Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia asiah_abdullah@ns.uitm.edu.my.; Faculty of Applied Sciences, Universiti Teknologi MARA 72500 Kuala Pilah Negeri Sembilan Malaysia., Abd Gani SS; Department of Agriculture Technology, Faculty of Agriculture, Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia ssalwaag@upm.edu.my ssalwa.abdgani@gmail.com +60 389474945.; Halal Products Research Institute, Universiti Putra Malaysia, Putra Infoport 43400 UPM Serdang Selangor Malaysia., Yun Hin TY; Department of Chemistry, Faculty of Science, Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia asiah_abdullah@ns.uitm.edu.my., Haiyee ZA; Faculty of Applied Sciences, Universiti Teknologi MARA 40450 Shah Alam Selangor Malaysia., Zaidan UH; Halal Products Research Institute, Universiti Putra Malaysia, Putra Infoport 43400 UPM Serdang Selangor Malaysia.; Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia., Kassim MA; Chemistry Department, Faculty of Science, University of Malaya 50603 Kuala Lumpur Malaysia.; Research Centre for Carbon Dioxide and Utilisation, School of Science and Technology, Universiti Putra Malaysia No. 5, Jalan Universiti Bandar Sunway 47500 Selangor Malaysia., Effendi Halmi MI; Department of Land Management, Faculty of Agriculture, Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia.
Jazyk:	angličtina
Zdroj:	RSC advances [RSC Adv] 2019 Feb 14; Vol. 9 (10), pp. 5599-5609. Date of Electronic Publication: 2019 Feb 14 (Print Publication: 2019).
DOI:	10.1039/c8ra09418g
Abstrakt:	Esters were synthesized via the alcoholysis of red pitaya seed oil with oleyl alcohol catalyzed by immobilized lipase, Lipozyme RM IM. The effects of synthesis parameters, including temperature, time, substrate molar ratio and enzyme loading, on the yield and productivity of esters were assessed using a central composite response surface design. The optimum yield and productivity were predicted to be about 80.00% and 0.58 mmol h -1 , respectively, at a synthesis temperature of 50.5 °C, time of 4 h, substrate molar ratio of 3.4 : 1 and with 0.17 g of enzyme. Esters were synthesized under the optimum synthesis conditions; it was found that the average yield and productivity were 82.48 ± 4.57% and 0.62 ± 0.04 mmol h -1 , respectively, revealing good correspondence with the predicted values. The main esters were oleyl linoleate, oleyl oleate, oleyl palmitate and oleyl stearate. The synthesized esters exhibited no irritancy effects and their physicochemical properties showed their suitability for use as cosmeceutical ingredients. Competing Interests: There are no conflicts to declare. (This journal is © The Royal Society of Chemistry.)
Databáze:	MEDLINE
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