Multiple and Diffuse Gliomas by 18F-Fluorocholine PET/CT: Two Sides of the Same Coin.

Autor: García Vicente AM; From the Nuclear Medicine Department, University General Hospital., Pérez-Beteta J; Mathematical Oncology Laboratory, Castilla-La Mancha University, Ciudad Real, Spain., Bosque JJ; Mathematical Oncology Laboratory, Castilla-La Mancha University, Ciudad Real, Spain., Soriano Castrejón ÁM; From the Nuclear Medicine Department, University General Hospital., Pérez-García VM; Mathematical Oncology Laboratory, Castilla-La Mancha University, Ciudad Real, Spain.
Jazyk: angličtina
Zdroj: Clinical nuclear medicine [Clin Nucl Med] 2022 Jun 01; Vol. 47 (6), pp. e457-e465. Date of Electronic Publication: 2022 Mar 30.
DOI: 10.1097/RLU.0000000000004145
Abstrakt: Abstract: Gliomas are characterized by an inherent diffuse and irregular morphology that prevents defining a boundary between tumor and healthy tissue, both in imaging assessment and surgical field. The effective identification of the extent of the disease in diffuse and multiple gliomas is crucial for their management but doing so by radiological means can be challenging. We present a broad spectrum of diffuse and multiple gliomas using 18F-fluorocholine PET/CT, demonstrating the potential of metabolic imaging in the evaluation of these gliomas, with implications in patient clinical management and outcome.
Competing Interests: Conflicts of interest and sources of funding: J.P.B. and V.M.P.-G. were partially funded by the Ministerio de Economía y Competitividad/FEDER, Spain (grant number MTM2015-71200-R), Junta de Comunidades de Castilla-La Mancha (grant number SBPLY/17/180501/000154), and James S. McDonnell Foundation 21st Century Science Initiative in Mathematical and Complex Systems Approaches for Brain Cancer (collaborative awards 220020560 and 220020450). The other authors have no conflicts of interest or sources of funding to declare.
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Databáze: MEDLINE
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