Dynamic changes in signal-averaged P wave after catheter ablation of atrial fibrillation.

Autor: Yugo D; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Cardiovascular Department, Faculty of Medicine University of Indonesia, Jakarta, Indonesia., Kuo MJ; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Hu YF; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Liu CM; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Lin YJ; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Chang SL; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Lo LW; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Chao TF; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Chung FP; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Liao JN; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Chang TY; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Lin CY; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Tuan TC; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Kuo L; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Liu SH; Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Ton AN; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Chhay C; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Elimam A; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Chen SA; Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.; Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan, ROC.
Jazyk: angličtina
Zdroj: Journal of the Chinese Medical Association : JCMA [J Chin Med Assoc] 2022 May 01; Vol. 85 (5), pp. 549-553. Date of Electronic Publication: 2022 May 02.
DOI: 10.1097/JCMA.0000000000000709
Abstrakt: Background: The comprehensive surveillance for interval changes in signal-averaged P-wave (SAPW) after pulmonary vein isolation (PVI) remains lacking. We aimed to analyze the SAPW parameters before and after PVI and explored their link to the left atrial electrical properties.
Methods: Eighteen patients with paroxysmal atrial fibrillation receiving primary catheter ablation were enrolled. SAPW parameters, including root mean square voltages in the last 40, 30, and 20 ms (RMS40, RMS30, and RMS20, respectively), the total P-wave (RMSt), the integral of P-wave potentials (Int-p), and P-wave duration (fPWD), were measured before and after PVI and correlated to the left atrial activation time (LAT) and mean left atrial voltage (LAV) from electro-anatomical mapping.
Results: Compared with the SAPW before PVI, fPWD (before vs after PVI: 144.1 ± 5.2 vs 135.1 ± 11.9 ms, p = 0.02), Int-p (687.4 ± 173.1 vs 559 ± 202.5 mVms, p = 0.01), and RMSt (6.44 ± 1.3 vs 5.44 ± 2.0 mV, p = 0.04) all decreased after PVI. RMS20, RMS30, and RMS40 showed no significant difference. Similarly, LAT (97.5 ± 9.3 vs 90.5 ± 9.3 ms, p = 0.008) and LAV (1.37 ± 0.27 vs 0.96 ± 0.31 mV, p = 0.001) decreased after PVI. Although consistent changes after PVI were observed between SAPW parameters and LAT or LAV, no linear correlation was observed among them.
Conclusion: The consistent changes in SAPW and left atrial electrical properties after PVI suggest that SAPW may be used as a noninvasive tool to monitor the responses to PVI.
Competing Interests: Conflicts of interest: Dr. Shih-Ann Chen, an editorial board member at Journal of the Chinese Medical Association, had no role in the peer review process of or decision to publish this article. The other authors declare that they have no conflicts of interest related to the subject matter or materials discussed in this article.
(Copyright © 2022, the Chinese Medical Association.)
Databáze: MEDLINE