Myocardial Infarction With Non-obstructive Coronary Arteries: An Updated Overview of Pathophysiology, Diagnosis, and Management.
| Autor: | Khan A; Internal Medicine, Ascension St. John Hospital, Detroit, USA., Lahmar A; Medicine, Faculty of Medicine and Pharmacy/Mohammed VI University Hospital, Oujda, MAR., Riasat M; Internal Medicine, Icahn School of Medicine Mount Sinai Beth Israel, New York, USA., Ehtesham M; Internal Medicine, Albany Medical Center, Albany, USA., Asif H; Internal Medicine, Woodhull Medical Center, New York, USA., Khan W; Internal Medicine, Faisalabad Medical University, Faisalabad, PAK., Haseeb M; Internal Medicine, Bahria International Hospital, Lahore, PAK.; Internal Medicine, Jinnah Hospital Lahore, Lahore, PAK., Boricha H; Internal Medicine, University of Pittsburgh Medical Center (UPMC) McKeesport Hospital, Pittsburgh, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 Mar 29; Vol. 14 (3), pp. e23602. Date of Electronic Publication: 2022 Mar 29 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.23602 |
| Abstrakt: | Myocardial infarction with non-obstructive coronary arteries (MINOCA) refers to acute myocardial infarction with normal or near-normal coronary arteries. The MINOCA is a heterogeneous group of conditions, and possible etiologies are coronary artery spasm, spontaneous coronary artery dissection, coronary thromboembolism, coronary plaque disruption, coronary microvascular dysfunction, supply and demand mismatch. It is more common in young adults, with women having a higher chance of getting MINOCA than men. Considering MINOCA as a clinically dynamic working diagnostic that needs further investigation rather than a "true" diagnosis is proposed. Optical coherence tomography (OCT), intravenous ultrasound (IVUS), cardiac MRI may be required to stratify the underlying mechanism. Due to the lack of evidence-based literature and prospective randomized controlled studies, therapeutic management is limited. Consequently, the strategy is patient-specific. The prognosis of MINOCA patients remains unclear and depends upon the underlying etiology. This article aims to review the literature about various aspects of MINOCA, including pathophysiology, diagnosis, prognosis, and treatment. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Khan et al.) |
| Databáze: | MEDLINE |
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