SGLT inhibitors as antidiabetic agents: a comprehensive review.

Autor: Kshirsagar RP; Yashodeep Institute of Pharmacy Aurangabad Maharashtra India - 431007., Kulkarni AA; Y. B. Chavan College of Pharmacy Aurangabad Maharashtra India - 431001 jnsangshetti@rediffmail.com., Chouthe RS; Srinath Institute of Pharmaceutical Education and Research Bajaj Nagar Waluj Aurangabad 431136 India., Pathan SK; Y. B. Chavan College of Pharmacy Aurangabad Maharashtra India - 431001 jnsangshetti@rediffmail.com., Une HD; Y. B. Chavan College of Pharmacy Aurangabad Maharashtra India - 431001 jnsangshetti@rediffmail.com., Reddy GB; Department of Biochemistry, National Institute of Nutrition (ICMR) Hyderabad Telangana India - 500007., Diwan PV; Maratha Mandal Research Centre Belagavi Karnataka India - 590019., Ansari SA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University Po Box 2454 Riyadh 11451 Saudi Arabia., Sangshetti JN; Y. B. Chavan College of Pharmacy Aurangabad Maharashtra India - 431001 jnsangshetti@rediffmail.com.
Jazyk: angličtina
Zdroj: RSC advances [RSC Adv] 2020 Jan 09; Vol. 10 (3), pp. 1733-1756. Date of Electronic Publication: 2020 Jan 09 (Print Publication: 2020).
DOI: 10.1039/c9ra08706k
Abstrakt: Diabetes is one of the most common disorders that substantially contributes to an increase in global health burden. As a metabolic disorder, diabetes is associated with various medical conditions and diseases such as obesity, hypertension, cardiovascular diseases, and atherosclerosis. In this review, we cover the scientific studies on sodium/glucose cotransporter (SGLT) inhibitors published during the last decade. Our focus on providing an exhaustive overview of SGLT inhibitors enabled us to present their chemical classification for the first time.
Competing Interests: There are no conflicts of interest to declare.
(This journal is © The Royal Society of Chemistry.)
Databáze: MEDLINE