3-(Bromoacetyl)coumarins: unraveling their synthesis, chemistry, and applications.

Autor:	Abdou MM; Egyptian Petroleum Research Institute Nasr City Cairo 11727 Egypt moaz.chem@gmail.com., Abu-Rayyan A; Faculty of Science, Applied Science Private University P. O. BOX 166 Amman 11931 Jordan., Bedir AG; Egyptian Petroleum Research Institute Nasr City Cairo 11727 Egypt moaz.chem@gmail.com., Abdel-Fattah S; Egyptian Petroleum Research Institute Nasr City Cairo 11727 Egypt moaz.chem@gmail.com., Omar AMA; Egyptian Petroleum Research Institute Nasr City Cairo 11727 Egypt moaz.chem@gmail.com., Ahmed AA; Department of Chemistry, Faculty of Science, Al-Azhar University Cairo 11884 Egypt., El-Desoky EI; Department of Chemistry, Faculty of Science, Mansoura University Mansoura 35516 Egypt., Ghaith EA; Department of Chemistry, Faculty of Science, Mansoura University Mansoura 35516 Egypt.
Jazyk:	angličtina
Zdroj:	RSC advances [RSC Adv] 2021 Nov 29; Vol. 11 (61), pp. 38391-38433. Date of Electronic Publication: 2021 Nov 29 (Print Publication: 2021).
DOI:	10.1039/d1ra05574g
Abstrakt:	This review emphasizes recent developments in synthetic routes of 3-(bromoacetyl)coumarin derivatives. Also, chemical reactions of 3-(bromoacetyl)coumarins as versatile building blocks in the preparation of critical polyfunctionalized heterocyclic systems and other industrially significant scaffolds are described. Recent advances of 3-(bromoacetyl)coumarins as attractive starting points towards a wide scale of five and six-membered heterocyclic systems such as thiophenes, imidazoles, pyrazoles, thiazoles, triazoles, pyrans, pyridines, thiadiazins as well as fused heterocyclic systems have been reported. Additionally, this review covers a wide range of analytical chemistry, fluorescent sensors, and biological applications of these moieties, covering the literature till May 2021. Competing Interests: There are no conflicts to declare. (This journal is © The Royal Society of Chemistry.)
Databáze:	MEDLINE
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