Impact of creative art therapy on fatigue and quality of life in patients treated for localized breast cancer: A randomized study.

Autor: Joly F; Department of Oncology, UNICANCER, Centre François Baclesse, Caen, France.; INSERM, U1086, Caen, France.; Université de Caen Basse-Normandie, UMR-S1077, Caen, France.; Department of Oncology, CHU de Caen, Caen, France., Pasquier D; UNICANCER, Centre Oscar Lambret, Lille, France.; Lille University, CRIStAL UMR, Lille, France., Levy C; Department of Oncology, UNICANCER, Centre François Baclesse, Caen, France., Mousseau M; Department of Oncology, CHU de Grenoble, Grenoble, France., D'Almeida MC; Department of Oncology, UNICANCER, Centre François Baclesse, Caen, France., Noal S; Department of Oncology, UNICANCER, Centre François Baclesse, Caen, France., Le Tinier F; Department of Oncology, CHU de Grenoble, Grenoble, France., Geffrelot J; Department of Oncology, UNICANCER, Centre François Baclesse, Caen, France., Ciais C; Department of Oncology, UNICANCER, Centre Antoine Lacassagne, Nice, France., Szymczak V; UNICANCER, Centre Oscar Lambret, Lille, France.; Lille University, CRIStAL UMR, Lille, France., Leon C; Department of Oncology, UNICANCER, Centre Henri Becquerel, Rouen, France., Rousselot MP; Department of Oncology, UNICANCER, Centre Antoine Lacassagne, Nice, France., Darbas S; Department of Oncology, CHU de Grenoble, Grenoble, France., Hanzen C; Department of Oncology, UNICANCER, Centre Henri Becquerel, Rouen, France., Heutte N; Department of Clinical Research, UNICANCER, Centre François Baclesse, Caen, France.
Jazyk: angličtina
Zdroj: Psycho-oncology [Psychooncology] 2022 Aug; Vol. 31 (8), pp. 1412-1419. Date of Electronic Publication: 2022 May 13.
DOI: 10.1002/pon.5940
Abstrakt: Background: Art therapy (AT) as supportive care may help patients cope with cancer treatments. This non-blinded randomized trial assessed the impact of creative AT on severe fatigue and quality of life (QoL) in localized breast cancer patients undergoing irradiation.
Material and Methods: 320 patients were randomized to an AT group (ATG; 8 weekly sessions starting during irradiation) or to a standard group (SG). The primary endpoint was severe global fatigue (Functional Assessment of Chronic Therapy Fatigue subscale score <37) at 1 month post-irradiation. Quality of life (Fact-B), anxiety/depression (Hospital Anxiety and Depression Scale (HADS)) and different dimensions of fatigue 20-item Multidimensional Fatigue Inventory (MFI-20) were assessed at 1, 6 and 12 months post-irradiation. The secondary endpoints, fatigue among patients treated with chemotherapy, QoL (Fact-B), anxiety/depression (HADS) and different dimensions of fatigue (MFI-20) at 1, 6 and 12 months post-irradiation (with post hoc analysis in patients with treated with chemotherapy) were also assessed.
Results: 82% of patients completed ≥8 sessions. Severe initial global fatigue was observed in 43% of patients in each group, and among in 64% of patients whose treatment protocol contained chemotherapy. At 1 month post-irradiation, 45% in the ATG and 57% of patients in the SG reported severe global fatigue (p = 0.37); among patients with initial severe mental fatigue (MFF), 79% and 44% had improved MFF (p = 0.007) respectively; similarly 79% and 44% with initial poor motivation had better mental motivation (p = 0.03). At 6 and 12 months, social well-being scores in the ATG were higher (21.3 and 21.4 vs. 19.8 and 19.2, p = 0.05 and p < 0.01) with a significant improvement for patients who had chemotherapy (41% vs. 18%, p = 0.017). A positive association was observed between the number of AT sessions, fatigue and QoL (p < 0.01).
Conclusion: AT did not significantly improve global severe fatigue among all cancer participants 1 month after radiation therapy, however it had a positive impact on social well-being and may improve MFF and motivation.
(© 2022 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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