SARS-CoV-2 Infection Rates Following Use of Regular Compared With Defective Respirators When Caring for COVID-19 Patients: A Retrospective Follow-up Study.

Autor:	Kolstad HA; Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.; Institute of Clinical Medicine, Aarhus University, DK-8200 Aarhus N, Denmark., Frydenberg M; Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark., Nielsen KJ; Department of Occupational Medicine, Danish Ramazzini Centre, Goedstrup Hospital, DK-7400 Herning, Denmark., Schlünssen V; Department of Public Health, Work, Environment and Health, Danish Ramazzini Centre, Aarhus University, DK-8000 Aarhus C, Denmark., Biering K; Department of Occupational Medicine, Danish Ramazzini Centre, Goedstrup Hospital, DK-7400 Herning, Denmark., Kjærsgaard M; Department of Clinical Microbiology, Aarhus University Hospital, DK-8200 Aarhus N, Denmark., Vestergaard JM; Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark., Würtz ET; Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark., Pugdahl K; Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark., Würtz AML; Department of Public Health, Work, Environment and Health, Danish Ramazzini Centre, Aarhus University, DK-8000 Aarhus C, Denmark., Hansen KK; Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark., Jespersen S; Department of Infectious Diseases, Aarhus University Hospital, DK-8200 Aarhus N, Denmark., Kragh Thomsen M; Department of Clinical Microbiology, Aarhus University Hospital, DK-8200 Aarhus N, Denmark., Sørensen MM; Department of Infectious Diseases, Aarhus University Hospital, DK-8200 Aarhus N, Denmark., Ellermann-Eriksen S; Department of Clinical Microbiology, Aarhus University Hospital, DK-8200 Aarhus N, Denmark., Dvinge Redder J; Business Intelligence, Central Denmark Region, DK-8200 Aarhus N, Denmark., Storgaard M; Department of Infectious Diseases, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.
Jazyk:	angličtina
Zdroj:	Annals of work exposures and health [Ann Work Expo Health] 2023 Jan 12; Vol. 67 (1), pp. 141-146.
DOI:	10.1093/annweh/wxac031
Abstrakt:	Background: There is strong observational evidence that respirators are highly effective in protecting the users from being infected with Middle East respiratory syndrome and severe acute respiratory syndrome coronavirus (SARS-CoV), but the evidence for SARS-CoV-2 during daily work is limited. This study utilized a subset of healthcare workers' temporary use of a new brand respirator with frequent defects when caring for coronavirus disease 2019 (COVID-19) patients to assess the protective effect of regular respirators against SARS-CoV-2 infection. Methods: We retrospectively followed 463 participants wearing a regular respirator and 168 wearing the new brand respirator day-by-day when caring for COVID-19 patients until testing polymerase chain reaction positive for SARS-CoV-2 between 27th December 2020 and 14th January 2021. Results: We observed seven and eight incident SARS-CoV-2-infected cases. This corresponded with daily infection rates of 0.2 and 0.5%, an incidence rate ratio of 0.4 [95% confidence interval (CI) 0.1; 1.0], and an incidence rate difference of 0.3% (95% CI -0.1; 0.8) when comparing a regular with the new brand respirator. Discussion: We regard the new brand respirator a sham intervention, and this study thus provides further evidence for the protective effect of respirators when exposed to SARS-CoV-2 virus. (© The Author(s) 2022. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.)
Databáze:	MEDLINE
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