Solid phase extraction based on trimethylsilyloxy silica aerogel.

Autor:	Prasanna VL; The Water Research Center, The Hydro-Chemistry Laboratory, Porter School for Environment and Earth Sciences, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University Tel Aviv 69978 Israel droravi@tauex.tau.ac.il., Gozlan I; The Water Research Center, The Hydro-Chemistry Laboratory, Porter School for Environment and Earth Sciences, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University Tel Aviv 69978 Israel droravi@tauex.tau.ac.il., Kaplan A; The Water Research Center, The Hydro-Chemistry Laboratory, Porter School for Environment and Earth Sciences, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University Tel Aviv 69978 Israel droravi@tauex.tau.ac.il., Zachor-Movshovitz D; The Water Research Center, The Hydro-Chemistry Laboratory, Porter School for Environment and Earth Sciences, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University Tel Aviv 69978 Israel droravi@tauex.tau.ac.il., Avisar D; The Water Research Center, The Hydro-Chemistry Laboratory, Porter School for Environment and Earth Sciences, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University Tel Aviv 69978 Israel droravi@tauex.tau.ac.il.
Jazyk:	angličtina
Zdroj:	RSC advances [RSC Adv] 2021 May 24; Vol. 11 (30), pp. 18617-18622. Date of Electronic Publication: 2021 May 24 (Print Publication: 2021).
DOI:	10.1039/d1ra01803e
Abstrakt:	Solid-phase extraction (SPE) based on trimethylsilyloxy-modified silica aerogel was developed for extraction of chemotherapeutic drugs from water. The developed method is easy and affordable, can be performed in separating funnel and does not require a vacuum and SPE manifold. The extraction and recovery of cyclophosphamide (CYP), dexamethasone (DEX), and paclitaxel (TAX) by the aerogel from water were investigated. The factors governing the extraction efficiency such as sample pH, sample volume, volume of eluent and concentration of analytes were studied. The LOD and LOQ of the developed method were calculated and linearity was found in the range of 4-100 μg L -1 . The extraction efficiency of the aerogel was compared to that of other SPE cartridges, Oasis HLB, Strata-X-C, C18 and polymeric reversed phase, and the aerogel showed similar or better performance than the other commercial cartridges available on the market. The developed method was also used to extract chemotherapeutic drugs spiked in hospital wastewater. Competing Interests: Authors declare no conflict of interest. (This journal is © The Royal Society of Chemistry.)
Databáze:	MEDLINE
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