[Morphological substantiation of laparoscopic suturing of stomach ulcer with formation of a covered perforation].

Autor:	Sazhin IV; Pirogov Russian National Research Medical University, Moscow, Russia.; Buyanov Moscow City Clinical Hospital, Moscow, Russia., Khripun AI; Pirogov Russian National Research Medical University, Moscow, Russia., Salikov AV; Pirogov Russian National Research Medical University, Moscow, Russia.; Buyanov Moscow City Clinical Hospital, Moscow, Russia., Shurygin SN; Buyanov Moscow City Clinical Hospital, Moscow, Russia.; Peoples' Friendship University of Russia, Moscow, Russia., Tsulaya AZ; Buyanov Moscow City Clinical Hospital, Moscow, Russia., Petrenko NV; Buyanov Moscow City Clinical Hospital, Moscow, Russia., Asratyan SA; Buyanov Moscow City Clinical Hospital, Moscow, Russia., Vaganov AG; Bauman Moscow City Clinical Hospital No. 29, Moscow, Russia., Alimov AN; Pirogov Russian National Research Medical University, Moscow, Russia.; Buyanov Moscow City Clinical Hospital, Moscow, Russia., Isaeva DA; Ivanovo State Medical Academy, Moscow, Russia.
Jazyk:	ruština
Zdroj:	Khirurgiia [Khirurgiia (Mosk)] 2022 (4), pp. 27-33.
DOI:	10.17116/hirurgia202204127
Abstrakt:	Objective: Morphological substantiation of laparoscopic suturing of gastric ulcer with formation of a covered perforation. Material and Methods: To analyze morphological tissue reaction in surgical area, we used 12 Chinchilla rabbits. All animals were divided into 2 groups by 6 animals. The main group enrolled rabbits undergoing suturing of perforated gastric ulcer with formation of a covered perforation by anterior stomach wall. In the control group, gastric perforation was sutured by conventional double-row suture. For histological analysis, 2 animals in each group were withdrawn from the experiment after 7, 14 and 21 days. We excised gastric wall within the area of perforation closure. Morphological data on healing process were compared between both groups. Results. S: Tomach deformation after 7 days was more severe in the main group compared to simple suturing. However, these differences were absent after 21 days. Morphological analysis revealed postoperative transmural necrosis after 7 days. Signs of early epithelialization were more obvious in the main group. After 21 postoperative days, we observed almost completely restored differentiation of stomach wall layers in both groups of animals.
Databáze:	MEDLINE
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