Analysis of trends in sepsis mortality in Brazil and by regions from 2010 to 2019.

Autor:	Almeida NRC; Universidade Federal do Pará. Faculdade de Medicina. Belém, PA, Brasil., Pontes GF; Centro Universitário do Estado do Pará. Faculdade de Medicina. Belém, PA, Brasil., Jacob FL; Universidade do Estado do Pará. Faculdade de Medicina. Belém, PA, Brasil., Deprá JVS; Universidade do Estado do Pará. Faculdade de Medicina. Belém, PA, Brasil., Porto JPP; Universidade do Estado do Pará. Faculdade de Medicina. Belém, PA, Brasil., Lima FR; Centro Universitário do Estado do Pará. Faculdade de Medicina. Belém, PA, Brasil., Albuquerque MRTC; Centro Universitário do Estado do Pará. Módulo de Interação em Saúde na Comunidade. Belém, PA, Brasil.
Jazyk:	English; Portuguese
Zdroj:	Revista de saude publica [Rev Saude Publica] 2022 Apr 22; Vol. 56, pp. 25. Date of Electronic Publication: 2022 Apr 22 (Print Publication: 2022).
DOI:	10.11606/s1518-8787.2022056003789
Abstrakt:	Objective: To characterize the profile of inpatients and trend of sepsis mortality in the Brazilian Unified Health System (SUS), throughout Brazil, and in its regions separately, from 2010 to 2019. Methods: Observational, analytical and retrospective study of secondary data obtained through consultation to the Sistema de Informação Hospitalar (Hospital Information System). All incoming septicemia notifications from January 1, 2010 to December 31, 2019 were included. The following sociodemographic variables were used: sex, age, race, region and federative unit of residence. For data analysis, we used mortality and hospitalization coefficient, relative risk and Joinpoint regression. Results: There were a total of 1,044,227 cases of sepsis in Brazil, yielding a mean prevalence coefficient of 51.3/100 thousand inhabitants. There were 463,000 deaths from sepsis recorded, with a mean prevalence coefficient of 22.8 deaths/100,000 inhabitants. The highest rates occurred among the elderly, of brown race, and there was no significant difference between genders. The Southeast region accounted for the highest rates of hospitalization and deaths. A general trend toward increased mortality was observed in the period studied. Conclusion: The heterogeneity of Brazil should be considered regarding socioeconomic and demographic characteristics, and differences in health investment and underreporting between regions, in order to understand the disease's epidemiological course. Finally, these findings should be correlated with other studies, in an effort to understand the behavior of the disease, and provide inputs for public and private policies in order to reduce the expressiveness of cases and deaths from sepsis in Brazil.
Databáze:	MEDLINE
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