Toward hypothesis-driven, personalized microbiome screening.
| Autor: | Sedrani C; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg., Wilmes P; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg. |
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| Jazyk: | angličtina |
| Zdroj: | Cell reports methods [Cell Rep Methods] 2022 Jan 24; Vol. 2 (1), pp. 100139. Date of Electronic Publication: 2022 Jan 24 (Print Publication: 2022). |
| DOI: | 10.1016/j.crmeth.2021.100139 |
| Abstrakt: | The human gut microbiome is crucial for human health and disease but exhibits extensive individual-level strain variation. Distinct strains encode and express different functions. The resulting emergent properties therefore differentially affect human health and disease in a personalized manner. Pryszlak et al. have made strides in tackling the challenge of genome-based microbiome screening which will ultimately yield strain-level understanding of the functional roles played by the human gut microbiome. Competing Interests: P.W. declares being listed as an inventor on patents PCT/EP2013/056607, PCT/EP2016/062024, PCT/US2017/061602, and PCT/EP2019/081424. (© 2021 The Author(s).) |
| Databáze: | MEDLINE |
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