Linking sporadic hospital clusters during a community surge of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) B.1.617.2 delta variant: The utility of whole-genome sequencing.

Autor:	Wee LE; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Ko KK; Department of Molecular Pathology, Singapore General Hospital, Singapore, Singapore.; Department of Microbiology, Singapore General Hospital, Singapore, Singapore.; Genome Institute of Singapore, A*STAR, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Conceicao EP; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore., Sim JX; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore.; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore., Rahman NA; Department of Microbiology, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Tan SY; Department of Microbiology, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Cao DY; Department of Microbiology, Singapore General Hospital, Singapore, Singapore., Chan KX; Department of Molecular Pathology, Singapore General Hospital, Singapore, Singapore., Aung MK; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore., Aung MO; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore., Yong Y; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore., Arora S; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore., How MKB; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore., Tan KY; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore., Lee LC; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore., Tan TT; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore., Wijaya L; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore., Sim JHC; Department of Microbiology, Singapore General Hospital, Singapore, Singapore., Suphavilai C; Genome Institute of Singapore, A*STAR, Singapore, Singapore., Venkatachalam I; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore.; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore., Ling ML; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore, Singapore.
Jazyk:	angličtina
Zdroj:	Infection control and hospital epidemiology [Infect Control Hosp Epidemiol] 2023 Jun; Vol. 44 (6), pp. 1014-1018. Date of Electronic Publication: 2022 Apr 27.
DOI:	10.1017/ice.2022.106
Abstrakt:	Sporadic clusters of healthcare-associated coronavirus disease 2019 (COVID-19) occurred despite intense rostered routine surveillance and a highly vaccinated healthcare worker (HCW) population, during a community surge of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) B.1.617.2 δ (delta) variant. Genomic analysis facilitated timely cluster detection and uncovered additional linkages via HCWs moving between clinical areas and among HCWs sharing a common lunch area, enabling early intervention.
Databáze:	MEDLINE
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