| Autor: |
Goong HJ; Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon 14584, Korea., Kim TJ; Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul 06351, Korea., Nam K; Department of Internal Medicine, Dankook University Hospital, Dankook University College of Medicine, Cheonan 31116, Korea., Park J; Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Korea., Kim JO; Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul 04401, Korea., Kim HG; Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul 04401, Korea., Ko BM; Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon 14584, Korea., Jeon SR; Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul 04401, Korea., Small Intestine Research Group Of The Korean Association For The Study Of Intestinal Diseases Kasid |
| Abstrakt: |
Device-assisted enteroscopy (DAE) enables the direct visualization of small bowel lesions with histological diagnosis; however, few studies have described the diagnostic performance of enteroscopic biopsy. We investigated the diagnostic performance of enteroscopic biopsy. We used a nationwide multicenter enteroscopy database to identify patients who underwent DAE with biopsy for small bowel diseases. The patients were classified into the tumor and non-tumor groups according to the final diagnosis. They were also divided into diagnostic and non-diagnostic groups based on the enteroscopic biopsy results. The clinical significance of the first biopsy and histological diagnostic yield of DAE were analyzed. Among the 112 procedures investigated, 32 (28.9%) were diagnosed with tumors, and 80 (71.7%) were diagnosed with non-tumor diseases. The overall histological diagnostic yield of DAE was 43.7%. The histological diagnostic yield was significantly higher in the tumor than in the non-tumor group (81.2% vs. 28.8%, p < 0.001). The mean number of biopsies was significantly higher in the diagnostic than in the non-diagnostic group (5.6 ± 3.3 vs. 3.7 ± 2.1, p = 0.001). In the diagnostic group, 87.7% of the cases were histologically confirmed at the first biopsy. Therefore, the first biopsy should be performed carefully. |
