Transmission of SARS-CoV-2 in the Population Living in High- and Low-Density Gradient Areas in Dhaka, Bangladesh.

Autor:	Satter SM; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Bhuiyan TR; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Abdullah Z; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Akhtar M; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Akter A; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Shafique SMZ; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Alam MR; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Chowdhury KIA; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Nazneen A; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Rimi NA; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Alamgir ASM; Institute of Epidemiology, Disease Control & Research, 44 Mohakhali, Dhaka 1212, Bangladesh., Rahman M; Institute of Epidemiology, Disease Control & Research, 44 Mohakhali, Dhaka 1212, Bangladesh., Khan FI; Institute of Epidemiology, Disease Control & Research, 44 Mohakhali, Dhaka 1212, Bangladesh., Shirin T; Institute of Epidemiology, Disease Control & Research, 44 Mohakhali, Dhaka 1212, Bangladesh., Flora MS; Directorate General of Health Services (DGHS), Mohakhali, Dhaka 1212, Bangladesh., Banu S; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Rahman M; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh., Rahman M; Global Health Development, EMPHNET, 69 Mohakhali, Dhaka 1212, Bangladesh., Qadri F; Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka 1212, Bangladesh.
Jazyk:	angličtina
Zdroj:	Tropical medicine and infectious disease [Trop Med Infect Dis] 2022 Mar 25; Vol. 7 (4). Date of Electronic Publication: 2022 Mar 25.
DOI:	10.3390/tropicalmed7040053
Abstrakt:	Community transmission of SARS-CoV-2 in densely populated countries has been a topic of concern from the beginning of the pandemic. Evidence of community transmission of SARS-CoV-2 according to population density gradient and socio-economic status (SES) is limited. In June−September 2020, we conducted a descriptive longitudinal study to determine the community transmission of SARS-CoV-2 in high- and low-density areas in Dhaka city. The Secondary Attack Rate (SAR) was 10% in high-density areas compared to 20% in low-density areas. People with high SES had a significantly higher level of SARS-CoV-2-specific Immunoglobulin G (IgG) antibodies on study days 1 (p = 0.01) and 28 (p = 0.03) compared to those with low SES in high-density areas. In contrast, the levels of seropositivity of SARS-CoV-2-specific Immunoglobulin M (IgM) were comparable (p > 0.05) in people with high and low SES on both study days 1 and 28 in both high- and low-density areas. Due to the similar household size, no differences in the seropositivity rates depending on the population gradient were observed. However, people with high SES showed higher seroconversion rates compared to people with low SES. As no difference was observed based on population density, the SES might play a role in SARS-CoV-2 transmission, an issue that calls for further in-depth studies to better understand the community transmission of SARS-CoV-2.
Databáze:	MEDLINE
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