Williams syndrome: reduced orienting to other's eyes in a hypersocial phenotype.

Autor: Kleberg JL; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institute and Stockholm Health Care Services, Region Stockholm, Sweden. johan.lundin.kleberg@ki.se.; Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden. johan.lundin.kleberg@ki.se., Riby D; Centre for Developmental Disorders, Department of Psychology, Durham University, Durham, United Kingdom., Fawcett C; Department of Psychology, Uppsala University, Uppsala, Sweden., Björlin Avdic H; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institute and Stockholm Health Care Services, Region Stockholm, Sweden., Frick MA; Department of Psychology, Uppsala University, Uppsala, Sweden.; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Brocki KC; Department of Psychology, Uppsala University, Uppsala, Sweden., Högström J; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institute and Stockholm Health Care Services, Region Stockholm, Sweden., Serlachius E; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institute and Stockholm Health Care Services, Region Stockholm, Sweden., Nordgren A; Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.; Department of Clinical genetics, Karolinska University Hospital, Stockholm, Sweden., Willfors C; Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.; Department of Clinical genetics, Karolinska University Hospital, Stockholm, Sweden.
Jazyk: angličtina
Zdroj: Journal of autism and developmental disorders [J Autism Dev Disord] 2023 Jul; Vol. 53 (7), pp. 2786-2797. Date of Electronic Publication: 2022 Apr 20.
DOI: 10.1007/s10803-022-05563-6
Abstrakt: Williams syndrome (WS) is a rare genetic condition associated with high sociability, intellectual disability, and social cognitive challenges. Attention to others' eyes is crucial for social understanding. Orienting to, and from other's eyes was studied in WS (n = 37, mean age = 23, age range 9-53). The WS group was compared to a typically developing comparison participants (n = 167) in stratified age groups from infancy to adulthood. Typically developing children and adults were quicker and more likely to orient to eyes than the mouth. This bias was absent in WS. The WS group had reduced peak saccadic velocities, indicating hypo-arousal. The current study indicates reduced orienting to others' eyes in WS, which may affect social interaction skills.
(© 2022. The Author(s).)
Databáze: MEDLINE
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