Real-time three-dimensional echocardiography for detection of cardiac sarcoidosis in the early stage: a cross-sectional single-centre study.
| Autor: | Cabuk AK; Department of Cardiology, Tepecik Training and Research Hospital, Izmir, Turkey., Cabuk G; Department of Cardiology, Tepecik Training and Research Hospital, Izmir, Turkey. |
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| Jazyk: | angličtina |
| Zdroj: | Acta cardiologica [Acta Cardiol] 2022 Oct; Vol. 77 (8), pp. 699-707. Date of Electronic Publication: 2022 Apr 20. |
| DOI: | 10.1080/00015385.2022.2064062 |
| Abstrakt: | Background: Sarcoidosis with cardiac involvement has a relatively high morbidity and mortality, and early diagnose of cardiac sarcoidosis is a critical issue. Systolic dyssynchrony index (SDI) measured by three-dimensional echocardiography was used in our study for detection of subclinical left ventricular (LV) systolic dysfunction in patients with sarcoidosis and normal LV function on two-dimensional echocardiography. Methods: Forty-four patients diagnosed with sarcoidosis (without clinically apparent cardiac involvement) and 44 healthy control subjects were included in this study. Two-dimensional echocardiographic parameters, also LV volumes and SDI measured by 3D echocardiography were analyzed in all participants. Results: While two-dimensional echocardiographic results of both study groups were similar; SDI_16 (SDI for 16 segments of LV) results were significantly higher in sarcoidosis group compared to healthy controls (6.99 ±5.02 vs 2.89 ± 1.32, p < 0.0001). Conclusion: SDI_16 was higher in patients with sarcoidosis compared to healthy controls probably due to patchy infiltration characteristic of the disease. This parameter could be used as a marker to identify patients with cardiac involvement of sarcoidosis in the early phase. |
| Databáze: | MEDLINE |
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