Systematic Review of Common Refractory Symptoms in the End-Of-Life Situation and Its Relation With Euthanasia.

Autor: Lucena A; Surgery Department, Faculty of Medicine, University of Lleida, Lleida, Spain., Yuguero O; Surgery Department, Faculty of Medicine, University of Lleida, Lleida, Spain.; Institut de Recerca Biomèdica de Lleida (IRBLLEIDA), Lleida, Spain.
Jazyk: angličtina
Zdroj: Omega [Omega (Westport)] 2024 Aug; Vol. 89 (3), pp. 1113-1127. Date of Electronic Publication: 2022 Apr 20.
DOI: 10.1177/00302228221089123
Abstrakt: Aim: To analyse the available evidence regarding refractory symptoms to treatment in patients receiving palliative/terminal healthcare.
Design: A systematic review of various databases between September and December 2020; Pubmed; Cochrane; Scopus and ScienceDirect. Study eligibility criteria: Studies published between 1 st January 2015 and 31 st of March 2020, in Spanish, English or Catalan conducted in elderly people or terminal patients. The study included systematic reviews, clinical trials and interventions.
Results: The search returned 782 articles, of which 22 articles were finally reviewed. Of the selected articles, 16 were systematic reviews and three were clinical trials. Three refractory symptoms are notable; breathlessness, delirium and existential suffering. There are various therapeutic approaches for the first two symptoms, but palliative sedation seems to be most effective for existential suffering.
Conclusions: Although palliative care enables controlling these symptoms effectively, and following a multidisciplinary approach, there remains a group of patients for whom euthanasia could save foreseeable suffering that is difficult to manage.
Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE