Hepatoprotective effects of flexirubin, a novel pigment from Chryseobacterium artocarpi, against carbon tetrachloride-induced liver injury: An in vivo study and molecular modeling.
Autor: | Mogadem A; Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 Skudai, Johor Bahru, Malaysia; Department of Chemistry, College of Science, Taibah University, Almadinah Almunawarah, Saudi Arabia., Naqvi A; Department of Chemistry, College of Science, Taibah University, Almadinah Almunawarah, Saudi Arabia., Almamary MA; Department of Chemistry, College of Science, Taibah University, Almadinah Almunawarah, Saudi Arabia., Ahmad WA; Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 Skudai, Johor Bahru, Malaysia. Electronic address: azlina@kimia.fs.utm.my., Jemon K; Department of Bioscience, Faculty of Science, Universiti Teknologi Malaysia, 81310 Skudai, Johor Bahru, Malaysia., El-Alfy SH; Department of Zoology, Faculty of Science, Ain Shams University, Cairo, Egypt; Department of Biology, College of Science, Taibah University, Almadinah Almunawarah, Saudi Arabia. Electronic address: s.helmy23@yahoo.com. |
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Jazyk: | angličtina |
Zdroj: | Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2022 Jun 01; Vol. 444, pp. 116022. Date of Electronic Publication: 2022 Apr 15. |
DOI: | 10.1016/j.taap.2022.116022 |
Abstrakt: | Liver injuries caused by various industrial chemicals represent a serious health concern worldwide. Flexirubins are a novel class of naturally occurring bacterial pigments whose bioactivity remains largely unexplored. The present study evaluated the hepatoprotective effects of flexirubin pigment extracted from the bacterium Chryseobacterium artocarpi against CCl (Copyright © 2022. Published by Elsevier Inc.) |
Databáze: | MEDLINE |
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