Identification of diffusion routes of O/EA-3 topotype of foot-and-mouth disease virus in Africa and Western Asia between 1974 and 2019 - a phylogeographic analysis.

Autor: Canini L; Paris Est University, ANSES, Laboratory for Animal Health, Epidemiology Unit, Maisons-Alfort, France., Blaise-Boisseau S; UMR 1161 Virology, INRA, ENVA, ANSES, Laboratory for Animal Health; EURL for Foot-and-mouth disease, Maisons-Alfort, France., Nardo AD; The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey GU24 ONF, UK., Shaw AE; The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey GU24 ONF, UK., Romey A; UMR 1161 Virology, INRA, ENVA, ANSES, Laboratory for Animal Health; EURL for Foot-and-mouth disease, Maisons-Alfort, France., Relmy A; UMR 1161 Virology, INRA, ENVA, ANSES, Laboratory for Animal Health; EURL for Foot-and-mouth disease, Maisons-Alfort, France., Bernelin-Cottet C; UMR 1161 Virology, INRA, ENVA, ANSES, Laboratory for Animal Health; EURL for Foot-and-mouth disease, Maisons-Alfort, France., Salomez AL; UMR 1161 Virology, INRA, ENVA, ANSES, Laboratory for Animal Health; EURL for Foot-and-mouth disease, Maisons-Alfort, France., Haegeman A; Sciensano, Scientific Direction of Infectious Diseases in Animals, Service for Exotic Viruses and Particular Diseases, Groeselenberg 99, Brussels, Belgium., Ularamu H; Virology Division, National Veterinary Research Institute, Vom, Nigeria., Madani H; Laboratoire Central Vétérinaire d'Alger, Institut National de Médecine Vétérinaire (INMV), Mohammadia, Algeria., Ouoba BL; Laboratoire national d'élevage of Ouagadougou, Burkina Faso., Zerbo HL; Laboratoire national d'élevage of Ouagadougou, Burkina Faso., Souare ML; Central Veterinary Diagnostic Laboratory in Conakry, Guinea., Boke CY; Laboratoire central vétérinaire de Bingerville (LCVB), Côte d'Ivoire., Eldaghayes I; Faculty of Veterinary Medicine, University of Tripoli, Libya., Dayhum A; Faculty of Veterinary Medicine, University of Tripoli, Libya., Ebou MH; Centre national d'élevage et de recherches vétérinaires, Nouakchott, Mauritanie., Abouchoaib N; Office National de Sécurité Sanitaire des produits Alimentaires (ONSSA), Rabat, Morocco., Sghaier S; Institute of Veterinary Research of Tunisia, Tunis, Tunisia., Lefebvre D; Sciensano, Scientific Direction of Infectious Diseases in Animals, Service for Exotic Viruses and Particular Diseases, Groeselenberg 99, Brussels, Belgium., DeClercq K; Sciensano, Scientific Direction of Infectious Diseases in Animals, Service for Exotic Viruses and Particular Diseases, Groeselenberg 99, Brussels, Belgium., Milouet V; The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey GU24 ONF, UK., Brocchi E; Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Brescia, Italy., Pezzoni G; Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Brescia, Italy., Nfon C; National Center for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, MB, Canada., King D; The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey GU24 ONF, UK., Durand B; Paris Est University, ANSES, Laboratory for Animal Health, Epidemiology Unit, Maisons-Alfort, France., Knowles N; The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey GU24 ONF, UK., Kassimi LB; UMR 1161 Virology, INRA, ENVA, ANSES, Laboratory for Animal Health; EURL for Foot-and-mouth disease, Maisons-Alfort, France., Benfrid S; UMR 1161 Virology, INRA, ENVA, ANSES, Laboratory for Animal Health; EURL for Foot-and-mouth disease, Maisons-Alfort, France.
Jazyk: angličtina
Zdroj: Transboundary and emerging diseases [Transbound Emerg Dis] 2022 Sep; Vol. 69 (5), pp. e2230-e2239. Date of Electronic Publication: 2022 Jun 03.
DOI: 10.1111/tbed.14562
Abstrakt: Foot-and-mouth disease (FMD) affects the livestock industry and socioeconomic sustainability of many African countries. The success of FMD control programs in Africa depends largely on understanding the dynamics of FMD virus (FMDV) spread. In light of the recent outbreaks of FMD that affected the North-Western African countries in 2018 and 2019, we investigated the evolutionary phylodynamics of the causative serotype O viral strains all belonging to the East-Africa 3 topotype (O/EA-3). We analyzed a total of 489 sequences encoding the FMDV VP1 genome region generated from samples collected from 25 African and Western Asian countries between 1974 and 2019. Using Bayesian evolutionary models on genomic and epidemiological data, we inferred the routes of introduction and migration of the FMDV O/EA-3 topotype at the inter-regional scale. We inferred a mean substitution rate of 6.64 × 10 -3  nt/site/year and we predicted that the most recent common ancestor for our panel of samples circulated between February 1967 and November 1973 in Yemen, likely reflecting the epidemiological situation in under sampled cattle-exporting East African countries. Our study also reinforces the role previously described of Sudan and South Sudan as a frequent source of FMDVs spread. In particular, we identified two transboundary routes of O/EA-3 diffusion: the first from Sudan to North-East Africa, and from the latter into Israel and Palestine AT; a second from Sudan to Nigeria, Cameroon, and from there to further into West and North-West Africa. This study highlights the necessity to reinforce surveillance at an inter-regional scale in Africa and Western Asia, in particular along the identified migration routes for the implementation of efficient control measures in the fight against FMD.
(© 2022 The Authors. Transboundary and Emerging Diseases published by Wiley-VCH GmbH.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje