Usefulness of optical enhancement endoscopy combined with magnification to improve detection of intestinal metaplasia in the stomach.

Autor: Sobrino-Cossío S; Hospital Ángeles del Pedregal, Ciudad de Mexico, Mexico.; Gástrica, Centro Avanzado en Endoscopia y Estudios Funcionales, Mexico City, Mexico., Teramoto-Matsubara O; Gástrica, Centro Avanzado en Endoscopia y Estudios Funcionales, Mexico City, Mexico.; Hospital ABC Ciudad de Mexico, Mexico., Emura F; Endoscopia Gastrointestinal Avanzada, EmuraCenter Latinoamérica y Departamento de Gastroenterología de la Universidad de la Sabana, Bogotá, Colombia.; Departamento de Gastroenterología de la Universidad de la Sabana, Chia, Cundinamarca, Colombia., Araya R; Servicio de Endoscopia y Gastroenterología de la Clínica Universidad de Los Andes y del Hospital Militar de Santiago y Clínica Universidad de los Andes, Santiago, Chile., Arantes V; Hospital das Clínicas, Faculdade de Medicina, Universidade Federal de Minas Gerais, Hospital Mater Dei Contorno, Belo Horizonte, Brasil., Galvis-García ES; Department of Endoscopy. Hospital General de Mexico 'Dr. Eduardo Liceaga,' Mexico City, Mexico., Meza-Caballero M; Gástrica, Centro Avanzado en Endoscopia y Estudios Funcionales, Mexico City, Mexico., García-Aguilar BS; Gástrica, Centro Avanzado en Endoscopia y Estudios Funcionales, Mexico City, Mexico., Reding-Bernal A; Research Division, Hospital General de Mexico 'Dr. Eduardo Liceaga,' Mexico City, Mexico., Uedo N; Osaka International Cancer Institute, Department of Gastrointestinal Oncology, Osaka, Japan.
Jazyk: angličtina
Zdroj: Endoscopy international open [Endosc Int Open] 2022 Apr 14; Vol. 10 (4), pp. E441-E447. Date of Electronic Publication: 2022 Apr 14 (Print Publication: 2022).
DOI: 10.1055/a-1759-2568
Abstrakt: Background and study aims  The light blue crest observed in narrow band imaging endoscopy has high diagnostic accuracy for diagnosis of gastric intestinal metaplasia (GIM). The objective of this prospective study was to evaluate the diagnostic accuracy of magnifying i-scan optical enhancement (OE) imaging for diagnosing the LBC sign in patients with different levels of risk for gastric cancer in a Mexican clinical practice. Patients and methods  Patients with a history of peptic ulcer and symptoms of dyspepsia or gastroesophageal reflux disease were enrolled. Diagnosis of GIM was made at the predetermined anatomical location and white light endoscopy and i-scan OE Mode 1 were captured at the two predetermined biopsy sites (antrum and pyloric regions). Results  A total of 328 patients were enrolled in this study. Overall GIM prevalence was 33.8 %. The GIM distribution was 95.4 % in the antrum and 40.5 % in the corpus. According to the Operative Link on Gastritis/Intestinal-Metaplasia Assessment staging system, only two patients (1.9 %) were classified with high-risk stage disease. Sensitivity, specificity, positive​ and negative predictive values, positive and negative likelihood ratios, and accuracy of both methods (95 % C. I.) were 0.50 (0.41-0.60), 0.55 (0.48-0.62), 0.36 (0.31-0.42), 0.68 (0.63-0.73), 1.12 (0.9-1.4), 0.9 (0.7-1.1), and 0.53 (0.43-0.60) for WLE, and 0.96 (0.90-0.99), 0.91 (0.86-0.94), 0.84 (0.78-0.89), 0.98 (0.94-0.99), 10.4 (6.8-16), 0.05 (0.02-0.12), and 0.93 (0.89-0.95), respectively. The kappa concordance was 0.67 and the reliability coefficient was 0.7407 for interobserver variability. Conclusions  Our study demonstrated the high performance of magnifying i-scan OE imaging for endoscopic diagnosis of GIM in Mexican patients.
Competing Interests: Competing interests Drs. Sobrino-Cossío and Teramoto-Matsubara are consultants for Endomédica S.A. de CV (distributor of Pentax Medical) in Mexico City. Dr. Emura is a speaker for Fuji. Dr. Uedo is a speaker for Olympus speaker.
(The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).)
Databáze: MEDLINE
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