Effects of oxytocin and vasopressin administration on human fathers' sensitive and challenging parenting: A randomized within-subject controlled trial.

Autor: Witte AM; Clinical Child & Family Studies, Faculty of Behavioral and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands. Electronic address: a.m.witte@vu.nl., de Moor MHM; Clinical Child & Family Studies, Faculty of Behavioral and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands., Majdandžić M; Research Institute of Child Development and Education, University of Amsterdam, Amsterdam, the Netherlands., Verhees MWFT; Quantitative Psychology and Individual Differences, KU Leuven, Leuven, Belgium., van IJzendoorn MH; Department of Psychology, Education, and Child Studies, Erasmus University Rotterdam, Rotterdam, the Netherlands; Research Department of Clinical, Education and Health Psychology, Faculty of Brain Sciences, UCL, London, UK., Bakermans-Kranenburg MJ; Clinical Child & Family Studies, Faculty of Behavioral and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands; Leiden Institute for Brain and Cognition, Leiden University Medical Center, Leiden, the Netherlands.
Jazyk: angličtina
Zdroj: Hormones and behavior [Horm Behav] 2022 Jun; Vol. 142, pp. 105175. Date of Electronic Publication: 2022 Apr 14.
DOI: 10.1016/j.yhbeh.2022.105175
Abstrakt: This randomized, double-blind, placebo-controlled within-subject study examined the effects of intranasal administration of oxytocin and vasopressin on fathers' sensitive and challenging parenting behaviors. Furthermore, we examined the moderating role of fathers' early childhood experiences. The sample consisted of 70 fathers with their 2- to 12-month-old infants. All fathers were assigned to each of the three experimental sessions (oxytocin, vasopressin, and placebo), on three separate days, with random order and intervening periods of one to two weeks. Sensitive and challenging parenting behaviors (CPB) were observed during a 10-minute free play task. Results showed no effects of vasopressin administration on paternal sensitivity. Fathers in the oxytocin condition were less sensitive than fathers in the placebo condition, and this effect was moderated by fathers' own childhood experiences: Fathers who reported higher levels of experienced parental love withdrawal were less sensitive in the oxytocin condition as compared to the placebo condition, whereas fathers with less experienced parental love withdrawal showed no difference in sensitivity between the oxytocin and placebo condition. No effects were found of oxytocin and vasopressin administration on fathers' CPB. Our results, although partly unexpected, are largely in line with previous literature showing that oxytocin administration can exert negative effects in individuals with adverse childhood experiences.
(Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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