Risk-Factors for Exposure Associated With SARS-CoV-2 Detection After Recent Known or Potential COVID-19 Exposures Among Patients Seeking Medical Care at a Large Urban, Public Hospital in Fulton County, Georgia - A Cross-Sectional Investigation.

Autor:	Smith-Jeffcoat SE; Centers for Disease Control and Prevention, Atlanta, GA, United States., Sleweon S; Centers for Disease Control and Prevention, Atlanta, GA, United States., Koh M; Centers for Disease Control and Prevention, Atlanta, GA, United States., Khalil GM; Centers for Disease Control and Prevention, Atlanta, GA, United States., Schechter MC; Emory University School of Medicine, Division of Infectious Diseases, Atlanta, GA, United States.; Grady Memorial Hospital, Atlanta, GA, United States., Rebolledo PA; Emory University School of Medicine, Division of Infectious Diseases, Atlanta, GA, United States.; Emory University School of Public Health, Hubert Department of Global Health, Atlanta, GA, United States., Kasinathan V; Emory University School of Medicine, Division of Infectious Diseases, Atlanta, GA, United States.; Grady Memorial Hospital, Atlanta, GA, United States., Hoffman A; Grady Memorial Hospital, Atlanta, GA, United States.; Emory University Nell Hodgson Woodruff School of Nursing, Atlanta, GA, United States., Rossetti R; Centers for Disease Control and Prevention, Atlanta, GA, United States., Shragai T; Centers for Disease Control and Prevention, Atlanta, GA, United States., O'Laughlin K; Centers for Disease Control and Prevention, Atlanta, GA, United States., Espinosa CC; Centers for Disease Control and Prevention, Atlanta, GA, United States., Bankamp B; Centers for Disease Control and Prevention, Atlanta, GA, United States., Bowen MD; Centers for Disease Control and Prevention, Atlanta, GA, United States., Paulick A; Centers for Disease Control and Prevention, Atlanta, GA, United States., Gargis AS; Centers for Disease Control and Prevention, Atlanta, GA, United States., Folster JM; Centers for Disease Control and Prevention, Atlanta, GA, United States., da Silva J; Centers for Disease Control and Prevention, Atlanta, GA, United States., Biedron C; Centers for Disease Control and Prevention, Atlanta, GA, United States., Stewart RJ; Centers for Disease Control and Prevention, Atlanta, GA, United States., Wang YF; Grady Memorial Hospital, Atlanta, GA, United States.; Emory University School of Medicine, Pathology & Laboratory Medicine, Atlanta, GA, United States., Kirking HL; Centers for Disease Control and Prevention, Atlanta, GA, United States., Tate JE; Centers for Disease Control and Prevention, Atlanta, GA, United States.
Jazyk:	angličtina
Zdroj:	Frontiers in public health [Front Public Health] 2022 Mar 24; Vol. 10, pp. 809356. Date of Electronic Publication: 2022 Mar 24 (Print Publication: 2022).
DOI:	10.3389/fpubh.2022.809356
Abstrakt:	We aimed to describe frequency of COVID-19 exposure risk factors among patients presenting for medical care at an urban, public hospital serving mostly uninsured/Medicare/Medicaid clients and risk factors associated with SARS-CoV-2 infection. Consenting, adult patients seeking care at a public hospital from August to November 2020 were enrolled in this cross-sectional investigation. Saliva, anterior nasal and nasopharyngeal swabs were collected and tested for SARS-CoV-2 using RT-PCR. Participant demographics, close contact, and activities ≤14 days prior to enrollment were collected through interview. Logistic regression was used to identify risk factors associated with testing positive for SARS-CoV-2. Among 1,078 participants, 51.8% were male, 57.0% were aged ≥50 years, 81.3% were non-Hispanic Black, and 7.6% had positive SARS-CoV-2 tests. Only 2.7% reported COVID-19 close contact ≤14 days before enrollment; this group had 6.79 adjusted odds of testing positive (95%CI = 2.78-16.62) than those without a reported exposure. Among participants who did not report COVID-19 close contact, working in proximity to ≥10 people (adjusted OR = 2.17; 95%CI = 1.03-4.55), choir practice (adjusted OR = 11.85; 95%CI = 1.44-97.91), traveling on a plane (adjusted OR = 5.78; 95%CI = 1.70-19.68), and not participating in an essential indoor activity (i.e., grocery shopping, public transit use, or visiting a healthcare facility; adjusted OR = 2.15; 95%CI = 1.07-4.30) were associated with increased odds of testing positive. Among this population of mostly Black, non-Hispanic participants seeking care at a public hospital, we found several activities associated with testing positive for SARS-CoV-2 infection in addition to close contact with a case. Understanding high-risk activities for SARS-CoV-2 infection among different communities is important for issuing awareness and prevention strategies. Competing Interests: YW, PR, VK, AH, and MS received funding for this study from the CDC Foundation. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Smith-Jeffcoat, Sleweon, Koh, Khalil, Schechter, Rebolledo, Kasinathan, Hoffman, Rossetti, Shragai, O'Laughlin, Espinosa, Bankamp, Bowen, Paulick, Gargis, Folster, da Silva, Biedron, Stewart, Wang, Kirking, Tate and CDC COVID-19 Emergency Response GA-10 Field.)
Databáze:	MEDLINE
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