Molecular methods unravel the biosynthetic potential of Trichoderma species.

Autor: Shenouda ML; OCI, BMWZ, Leibniz University of Hannover Schneiderberg 38 30167 Hannover Germany russell.cox@oci.uni-hannover.de.; Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University 21521 Egypt., Cox RJ; OCI, BMWZ, Leibniz University of Hannover Schneiderberg 38 30167 Hannover Germany russell.cox@oci.uni-hannover.de.
Jazyk: angličtina
Zdroj: RSC advances [RSC Adv] 2021 Jan 18; Vol. 11 (6), pp. 3622-3635. Date of Electronic Publication: 2021 Jan 18 (Print Publication: 2021).
DOI: 10.1039/d0ra09627j
Abstrakt: Members of the genus Trichoderma are a well-established and studied group of fungi, mainly due to their efficient protein production capabilities and their biocontrol activities. Despite the immense interest in the use of different members of this species as biopesticides and biofertilizers, the study of their active metabolites and their biosynthetic gene clusters has not gained significant attention until recently. Here we review the challenges and opportunities in exploiting the full potential of Trichoderma spp. for the production of natural products and new metabolic engineering strategies used to overcome some of these challenges.
Competing Interests: There are no conflicts to declare.
(This journal is © The Royal Society of Chemistry.)
Databáze: MEDLINE