Experiencing COVID-19 at a large district level hospital in Cape Town: A retrospective analysis of the first wave.

Autor:	Claassen N; Department of Internal Medicine, Karl Bremer Hospital, Cape Town, South Africa., van Wyk G; Department of Internal Medicine, Karl Bremer Hospital, Cape Town, South Africa., van Staden S; Department of Internal Medicine, Karl Bremer Hospital, Cape Town, South Africa., Basson MMD; Department of Internal Medicine, Karl Bremer Hospital, Cape Town, South Africa.
Jazyk:	angličtina
Zdroj:	Southern African journal of infectious diseases [S Afr J Infect Dis] 2022 Mar 29; Vol. 37 (1), pp. 317. Date of Electronic Publication: 2022 Mar 29 (Print Publication: 2022).
DOI:	10.4102/sajid.v37i1.317
Abstrakt:	Background: The coronavirus disease 2019 (COVID-19) pandemic in tertiary hospitals from South Africa and world wide have been well described, but limited data are published on the findings. This article aimed to describe patients admitted to a large district hospital in Cape Town, South Africa, during the first wave of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Infections. To compare the clinical features and further investigate survivors and deceased COVID-19 patients. Methods: A single centre retrospective review of clinical records and laboratory data of patients admitted with a positive SARS-CoV-2 polymerase chain reaction (PCR) from April 2020 to August 2020. Results: A total of 568 patients with a positive SARS-CoV-2 PCR were admitted to the study centre for one night or longer and of these patients 154 (27%) died of COVID-19. The median age of patients who died of COVID-19 was 66 years and 53 years for survivors. Hypertension, diabetes mellitus and obesity were the commonest comorbidities in patients who survived and died of COVID-19. There were no major differences when comparing the severity of infiltrates on chest X-rays (CXR) of COVID-19 survivors with deceased patients. More than half (58%) of deceased patients died within 3 days following admission to hospital. A substantial number of patients who died of COVID-19 had associated acute kidney injury ( n = 79, 51%). Conclusion: Acute kidney injury had a high prevalence amongst patients who died of COVID-19. Delays in transfer to intensive care unit (ICU), limited ICU capacity and disease severity contributed to a substantial number of patients dying within 3 days of admission. Competing Interests: The authors declare that they have no financial or personal relationships that may have inappropriately influenced them in writing this article. (© 2022. The Authors.)
Databáze:	MEDLINE
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