Using high-resolution contact networks to evaluate SARS-CoV-2 transmission and control in large-scale multi-day events.

Autor: Pung R; Ministry of Health, Singapore, Singapore. rachael.pung@lshtm.ac.uk.; Centre for the Mathematical Modelling of infectious Diseases, London School of Hygiene and Tropical Medicine, London, UK. rachael.pung@lshtm.ac.uk.; Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK. rachael.pung@lshtm.ac.uk., Firth JA; Department of Zoology, University of Oxford, Oxford, UK.; Merton College, University of Oxford, Oxford, UK., Spurgin LG; School of Biological Sciences, University of East Anglia, Norwich, UK., Lee VJ; Ministry of Health, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Kucharski AJ; Centre for the Mathematical Modelling of infectious Diseases, London School of Hygiene and Tropical Medicine, London, UK.; Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Jazyk: angličtina
Zdroj: Nature communications [Nat Commun] 2022 Apr 12; Vol. 13 (1), pp. 1956. Date of Electronic Publication: 2022 Apr 12.
DOI: 10.1038/s41467-022-29522-y
Abstrakt: The emergence of highly transmissible SARS-CoV-2 variants has created a need to reassess the risk posed by increasing social contacts as countries resume pre-pandemic activities, particularly in the context of resuming large-scale events over multiple days. To examine how social contacts formed in different activity settings influences interventions required to control Delta variant outbreaks, we collected high-resolution data on contacts among passengers and crew on cruise ships and combined the data with network transmission models. We found passengers had a median of 20 (IQR 10-36) unique close contacts per day, and over 60% of their contact episodes were made in dining or sports areas where mask wearing is typically limited. In simulated outbreaks, we found that vaccination coverage and rapid antigen tests had a larger effect than mask mandates alone, indicating the importance of combined interventions against Delta to reduce event risk in the vaccine era.
(© 2022. The Author(s).)
Databáze: MEDLINE
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