Clinical implementation of HyperArc.

Autor: Wong FHC; Waikato Regional Cancer Centre, Waikato Hospital, Pembroke Street, Hamilton, Waikato, 3204, New Zealand. Felix.Wong@waikatodhb.health.nz., Moleme PA; Waikato Regional Cancer Centre, Waikato Hospital, Pembroke Street, Hamilton, Waikato, 3204, New Zealand., Ali OA; Waikato Regional Cancer Centre, Waikato Hospital, Pembroke Street, Hamilton, Waikato, 3204, New Zealand., Mugabe KV; Waikato Regional Cancer Centre, Waikato Hospital, Pembroke Street, Hamilton, Waikato, 3204, New Zealand.
Jazyk: angličtina
Zdroj: Physical and engineering sciences in medicine [Phys Eng Sci Med] 2022 Jun; Vol. 45 (2), pp. 577-587. Date of Electronic Publication: 2022 Apr 11.
DOI: 10.1007/s13246-022-01123-5
Abstrakt: The aim of this study was to present our experience on clinical implementation of HyperArc including dosimetric comparison between VMAT and HyperArc plans and dosimetric verification of HyperArc. In this study, eleven previously treated cases of brain metastasis were selected from our brain stereotactic radiotherapy program. The cases were retrospectively planned using HyperArc technique and the plan quality was evaluated. In addition, dosimetric effects of HyperArc plan with different energies and using jaw tracking technique were evaluated. Furthermore, dosimetric verification of HyperArc plans was performed using ion chamber and radiochromic film. Our results of dosimetric comparison shows that HyperArc technique improved both conformity index and gradient index compared to VMAT plans. We also found that using 6MV flattening filter free (6MV-FFF) beam improves gradient index in HyperArc plans compared to using 6MV flattening filter beam. Furthermore, our results show that jaw tracking technique reduces the size of low dose volume while maintaining similar target coverage, conformity index, and gradient index. In our dosimetric verification study, results of ion chamber and film measurement indicate no significant difference between VMAT and HyperArc plans. In conclusion, HyperArc simplifies planning of stereotactic treatment for brain and improves the dosimetry in treatment plans. Additionally, HyperArc provides for a safe and efficient treatment delivery system for stereotactic treatments to brain.
(© 2022. Australasian College of Physical Scientists and Engineers in Medicine.)
Databáze: MEDLINE
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