Multimodal Evaluation of Voice Outcome in Early Glottic Cancers Treated With Definitive Radiotherapy.

Autor:	Trignani M; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., DI Pilla A; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Rosa C; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy.; Department of Neuroscience, Imaging and Clinical Sciences, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Borgia M; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Fasciolo D; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Gasparini L; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., DI Guglielmo F; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Allajbej A; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy., DI Francesco M; Speech Rehabilitation and Phoniatrics, 'Sant'Agostino' Centre, Fondazione Papa Paolo VI, Chieti, Italy., Falcone G; Speech Rehabilitation and Phoniatrics, 'Sant'Agostino' Centre, Fondazione Papa Paolo VI, Chieti, Italy., Vitullo F; Department of Otorinolaryngology, SS. Annunziata Hospital, Chieti, Italy., Croce A; Department of Otorinolaryngology, SS. Annunziata Hospital, Chieti, Italy., Genovesi D; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy.; Department of Neuroscience, Imaging and Clinical Sciences, 'G. D'Annunzio' University of Chieti, Chieti, Italy., Caravatta L; Department of Radiation Oncology, SS. Annunziata Hospital, 'G. D'Annunzio' University of Chieti, Chieti, Italy.
Jazyk:	angličtina
Zdroj:	Cancer diagnosis & prognosis [Cancer Diagn Progn] 2021 Jul 03; Vol. 1 (3), pp. 143-149. Date of Electronic Publication: 2021 Jul 03 (Print Publication: 2021).
DOI:	10.21873/cdp.10019
Abstrakt:	Background/aim: We employed a multimodal evaluation of voice outcome (MEVO) model to assess long-term voice outcome in early glottic cancer (EGC) patients treated with primary radiotherapy (RT). The model consisted of objective and subjective vocal evaluation during follow-up, by a dedicated Speech Pathologist and Speech Therapist. Patients and Methods: MEVO methodology includes Self-perception Voice Handicap Index (VHI-30), evaluation of parameters Grade (G), Roughness (R), Breathiness (B), Asthenia (A) and Strain (S) according to GRBAS scale, objective analysis and aerodynamics using the PRAAT software and laryngeal evaluation with videostroboscope (VS). Results: The MEVO methodology was described and tested on a sample of 10 EGCs submitted to definitive RT (total dose 66-70 Gy). Mean follow-up was 48.9 months (range=9-115). VHI was mild-moderate in 90% of patients; overall voice function (GRBAS) was normal-mildly impaired in 70% of patients; VS evaluation showed normal vocal cord motion in 90% of patients, but complete glottic closure in 60%. PRAAT scores confirmed these findings. Conclusion: A multidimensional voice evaluation is time consuming, but useful to objectify vocal impact of radiotherapy. The MEVO model allowed to quantify vocal dysfunction, showing a good objective vocal outcome. Competing Interests: The Authors report no conflicts of interest. (Copyright 2021, International Institute of Anticancer Research.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu