Survival, functional, and quality of life outcomes between total glossectomy with and without total laryngectomy: A narrative review.

Autor: Burnham AJ; Department of Otolaryngology - Head and Neck Surgery, Emory University School of Medicine, United States of America., Ottenstein L; Department of Otolaryngology - Head and Neck Surgery, Emory University School of Medicine, United States of America; The Winship Cancer Institute at Emory University, United States of America., Boyce BJ; Department of Otolaryngology - Head and Neck Surgery, Emory University School of Medicine, United States of America; The Winship Cancer Institute at Emory University, United States of America., Kaka AS; Department of Otolaryngology - Head and Neck Surgery, Emory University School of Medicine, United States of America; The Winship Cancer Institute at Emory University, United States of America., El-Deiry MW; Department of Otolaryngology - Head and Neck Surgery, Emory University School of Medicine, United States of America; The Winship Cancer Institute at Emory University, United States of America., Baddour HM; Department of Otolaryngology - Head and Neck Surgery, Emory University School of Medicine, United States of America; The Winship Cancer Institute at Emory University, United States of America., Patel MR; Department of Otolaryngology - Head and Neck Surgery, Emory University School of Medicine, United States of America; The Winship Cancer Institute at Emory University, United States of America., Gross JH; Department of Otolaryngology - Head and Neck Surgery, Emory University School of Medicine, United States of America; The Winship Cancer Institute at Emory University, United States of America., Schmitt NC; Department of Otolaryngology - Head and Neck Surgery, Emory University School of Medicine, United States of America; The Winship Cancer Institute at Emory University, United States of America. Electronic address: nicole.cherie.schmitt@emory.edu.
Jazyk: angličtina
Zdroj: American journal of otolaryngology [Am J Otolaryngol] 2022 May-Jun; Vol. 43 (3), pp. 103440. Date of Electronic Publication: 2022 Apr 05.
DOI: 10.1016/j.amjoto.2022.103440
Abstrakt: Background: A total glossectomy (TG) may be required for advanced tongue tumors. TG with total laryngectomy (TGL) may be indicated in some cases with tumor extension into the larynx or high risk of aspiration. Total glossectomy with laryngeal preservation (TGLP) may preserve phonation ability relative to TGL, yet TGLP may increase the risk of aspiration.
Methods: For this narrative review, we performed a comprehensive literature search of studies relevant to TG and TGL. Clinical studies investigating survival, functional outcomes, and quality of life in following TGLP or TGL were of particular interest.
Results: Few studies in the literature directly compare survival, functional, and quality of life (QOL) outcomes between TGLP and TGL. TGLP is associated with intelligible speech. However, studies investigating gastrostomy tube dependence following TGLP versus TGL have generated conflicting results.
Conclusion: Further research on functional and QOL outcomes in patients undergoing TGL or TGLP is needed.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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