Detection of the Omicron variant of SARS-CoV-2 in international travelers returning to Venezuela.

Autor: Jaspe RC; Laboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas, Miranda, Venezuela., Sulbaran Y; Laboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas, Miranda, Venezuela., Loureiro CL; Laboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas, Miranda, Venezuela., Moros ZC; Laboratorio de Biología de Virus, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela., Marulanda E; Laboratorio de Biología Molecular Casa Lab 2020, Caracas, Venezuela., Bracho F; Laboratorio de Biología Molecular Casa Lab 2020, Caracas, Venezuela., Ramírez NA; Laboratorio de Biología Molecular Tu Buen Doctor, Caracas, Venezuela., Canonico Y; Laboratorio de Biología Molecular Tu Buen Doctor, Caracas, Venezuela., D'Angelo P; Instituto Nacional de Higiene 'Rafael Rangel', Caracas, Miranda, Venezuela., Rodríguez L; Instituto Nacional de Higiene 'Rafael Rangel', Caracas, Miranda, Venezuela., Castro J; Policlínica Metropolitana, Caracas, Venezuela., Liprandi F; Laboratorio de Biología de Virus, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela., Rangel HR; Laboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas, Miranda, Venezuela., Pujol FH; Laboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas, Miranda, Venezuela. Electronic address: fhpujol@gmail.com.
Jazyk: angličtina
Zdroj: Travel medicine and infectious disease [Travel Med Infect Dis] 2022 Jul-Aug; Vol. 48, pp. 102326. Date of Electronic Publication: 2022 Apr 05.
DOI: 10.1016/j.tmaid.2022.102326
Abstrakt: Background: By the end of 2021, the SARS-CoV-2 Variant of Concern (VOC) Delta was predominant in most of the world. At the end of November, the Omicron variant was first detected in South Africa. This variant was immediately classified as VOC, due to the explosive increase of cases in South Africa, and the great number of mutations exhibited by this new lineage. Since then, Omicron VOC displaced Delta one in almost every country. Venezuela implemented in May 2021 molecular testing of all the passengers arriving at Venezuelan airports.
Methods: In this study, we analyzed the presence of variants of SARS-CoV-2 in those positive samples, by sequencing a small fragment of the Spike genomic region.
Results: The Omicron variant was found in passengers arriving to Venezuela from the beginning of December. Complete genome analysis confirmed the presence of the Omicron VOC. The detection of this VOC coincided with an unprecedented increase in the frequency of passengers with positive nucleic acid testing.
Conclusions: Genomic surveillance of samples for international travelers returning to Venezuela allowed us to rapidly detect the introduction of the Omicron variant in the country.
(Copyright © 2022 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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