| Autor: |
Pulido-Colina A; Universidad Nacional Federico Villarreal, Lima, Perú.; Universidad Nacional Mayor de San Marcos, Lima, Perú., Pastrana JS; Hospital Nacional Docente Madre-Niño San Bartolomé, Lima, Perú., Valencia-Bazalar E; Instituto de Medicina Tropical «Daniel A. Carrión», Departamento Académico de Microbiología Médica. Facultad de Medicina. Universidad Nacional Mayor de San Marcos, Lima, Perú., Apestegui MZ; Centro de Investigaciones Tecnológicas, Biomédicas y Medioambientales, Universidad Nacional Mayor de San Marcos, Lima, Perú. |
| Jazyk: |
Spanish; Castilian |
| Zdroj: |
Revista peruana de medicina experimental y salud publica [Rev Peru Med Exp Salud Publica] 2021 Oct-Dec; Vol. 38 (4), pp. 615-620. Date of Electronic Publication: 2022 Apr 01. |
| DOI: |
10.17843/rpmesp.2021.384.8726 |
| Abstrakt: |
The aim of the study was to molecularly identify virulence and macrolide resistance genes in clinical isolates of Streptococcus agalactiae (GBS), recovered in 2019 from vaginal discharge (n=9) and urine (n=22), from two health facilities in Lima. Identification and antimicrobial susceptibility were determined by the Vitek® 2 automated system, identification was confirmed phenotypically; macrolide resistance was determined by the D-test method. Identification of virulence genes (lmb, bca and rib) and macrolide resistance genes (ermB, ermTR and mefA) was carried out by polymerase chain reaction (PCR). The predominant macrolide resistance phenotype and genotype were cMLSb (12/31) and ermB (11/31); the most frequent virulence gene was lmb (23/31). All were sensitive to penicillin, ampicillin and vancomycin. These findings show the need to implement molecular epidemiology studies that allow adequate knowledge and follow-up of GBS in Peru. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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