Seroprevalence of Toxoplasma gondii and associated alterations in hematology and serum biochemistry of one-humped camels ( Camelus dromedarius ) in Pakistan.

Autor:	Shehzad A; Division of Microbiology, Faculty of Veterinary Medicine, University of Airlangga, Surabaya 60115, Indonesia.; Livestock and Dairy Development, Government of Punjab, Lahore, Pakistan., Masud A; Livestock and Dairy Development, Government of Punjab, Lahore, Pakistan.; Department of Microbiology, Faculty of Veterinary Sciences, University of Veterinary and Animal Sciences, Lahore, Pakistan., Fatima T; Department of Parasitology, Riphah College of Veterinary Sciences, Riphah International University, Lahore, Pakistan., Khan FM; Livestock and Dairy Development, Government of Punjab, Lahore, Pakistan., Rehman S; Division of Microbiology, Faculty of Veterinary Medicine, University of Airlangga, Surabaya 60115, Indonesia.; Department of Veterinary Public Health, Faculty of Veterinary Medicine, University of Airlangga, Surabaya 60115, Indonesia., Effendi MH; Department of Veterinary Public Health, Faculty of Veterinary Medicine, University of Airlangga, Surabaya 60115, Indonesia., Suwanti LT; Department Veterinary Parasitology, Faculty of Veterinary Medicine, University of Airlangga, Surabaya 60115, Indonesia., Khan I; Department of Clinical Sciences, Section of Epidemiology and Public Health, Jhang Campus, University of Veterinary and Animal Sciences, Lahore, Pakistan., Tyasningsih W; Division of Microbiology, Faculty of Veterinary Medicine, University of Airlangga, Surabaya 60115, Indonesia., Faisal S; Department of Pharmacy Practice, Faculty of Pharmacy, University of Airlangga Surabaya 60115, Indonesia., Abadeen ZU; Department of Pathology, University of Agriculture Faisalabad, Pakistan., Bibi S; Institute of Food Science and Nutrition, Faculty of Agriculture, University of Sargodha, Sargodha Division, Punjab, Pakistan.
Jazyk:	angličtina
Zdroj:	Veterinary world [Vet World] 2022 Jan; Vol. 15 (1), pp. 110-118. Date of Electronic Publication: 2022 Jan 23.
DOI:	10.14202/vetworld.2022.110-118
Abstrakt:	Background and Aim: Toxoplasma gondii is an intracellular protozoan that infects humans and animals. This study aimed to estimate the seroprevalence of T. gondii and the associated alterations in hematology and serum biochemistry of one-humped camels ( Camelus dromedarius ) in Mianwali district, Pakistan. Materials and Methods: A total of 350 blood samples were obtained from male and female camels of different ages (≤3 years old, 4-6 years old, and ≥7 years old). To validate T. gondii antibodies, the collected samples were subjected to indirect enzyme-linked immunosorbent assay using purified recombinant micronemal protein 3 as an antibody catching antigen. Results: The prevalence of T. gondii was 50.2% higher in male camels than in female camels (16.5%) (p<0.001). Furthermore, the prevalence of T. gondii in camels was directly proportional to age (p<0.001). It was 63.33% (57/90) in camels of ≥7 years of age, 32.54% in 4-6 years old age group, and 23.08% in ≤3 years old age group. The hematological analysis of infected camels revealed a significant increase in the values of glucocorticoid-remediable aldosteronism, lymphocyte percentage, monocyte percentage (MONO%), corpuscular hemoglobin (MCH), and procalcitonin. Furthermore, substantially higher levels of liver enzymes alanine aminotransferase, aspartate aminotransferase, and the macro-mineral potassium were found in the serum of T. gondii -infected camels. Conclusion: The seropositivity of T. gondii is directly associated with the age and sex of camels, which may be considered as potential risk factors. Furthermore, T. gondii infection directly impacts the hemato-biochemistry of infected camels. Competing Interests: The authors declare that they have no competing interests. (Copyright: © Shehzad, et al.)
Databáze:	MEDLINE
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