Selective and Sensitive Fluorometric Determination of Piroxicam Based on Nitrogen-doped Graphene Quantum Dots and Gold Nanoparticles Coated with Phenylalanine.

Autor: Moallemi Bahmani M; Department of Chemistry, Faculty of Science, Yazd University, Yazd, Iran., Haji Shabani AM; Department of Chemistry, Faculty of Science, Yazd University, Yazd, Iran. hshabani@yazd.ac.ir., Dadfarnia S; Department of Chemistry, Faculty of Science, Yazd University, Yazd, Iran. sdadfarnia@yazd.ac.ir., Afsharipour R; Department of Chemistry, Faculty of Science, Yazd University, Yazd, Iran.
Jazyk: angličtina
Zdroj: Journal of fluorescence [J Fluoresc] 2022 Jul; Vol. 32 (4), pp. 1337-1346. Date of Electronic Publication: 2022 Apr 02.
DOI: 10.1007/s10895-022-02907-4
Abstrakt: In this study, a sensitive fluorimetric method is proposed for the determination of piroxicam using nitrogen graphene quantum dots (N-GQDs) and gold nanoparticles coated with phenylalanine. The fluorescence emission of N-GQDs at 440 nm decreases with the increase of gold nanoparticles coated with phenylalanine. However, the addition of piroxicam causes the release of gold nanoparticles from the surface of quantum dots followed by the retrieval of the fluorescence emission of N-GQDs. Under the optimum conditions, the calibration graph was linear in the concentration range of 2.0-35.0 nmol L -1 for piroxicam with a limit of detection of 0.11 nmol L -1 . The developed method was successfully applied for the determination of piroxicam in urine and serum samples.
(© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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