Spatio-temporal dynamics of rabies and habitat suitability of the common marmoset Callithrix jacchus in Brazil.

Autor: Benavides JA; Doctorado en Medicina de la Conservación y Centro de Investigación para la Sustentabilidad, Facultad de Ciencias de la Vida, Universidad Andres Bello, República 440 Santiago, Chile.; MIVEGEC, IRD, CNRS, Université de Montpellier, Montpellier, France.; Departamento Higiene Veterinária e Saúde Pública, Faculdade de Medicina Veterinária e Zootecnia, Universidade Estadual Júlio de Mesquita Filho, Botucatu, Brazil., Raghavan RK; Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, United States of America.; Department of Public Health, School of Health Professions, University of Missouri, Columbia, Missouri, United States of America., Boere V; Institute of Humanities, Arts and Sciences, Federal University of Southern Bahia -UFSB, Itabuna, Brazil., Rocha S; Secretaria de Vigilância em Saúde (SVS), Ministério da Saúde, Brasilia, Brazil., Wada MY; Secretaria de Vigilância em Saúde (SVS), Ministério da Saúde, Brasilia, Brazil., Vargas A; Secretaria de Vigilância em Saúde (SVS), Ministério da Saúde, Brasilia, Brazil., Voietta F; Secretaria de Vigilância em Saúde (SVS), Ministério da Saúde, Brasilia, Brazil., de Oliveira E Silva I; Institute of Humanities, Arts and Sciences, Federal University of Southern Bahia -UFSB, Itabuna, Brazil., Leal S; Secretaria de saúde de Pernambuco, Recife, Brazil., de Castro A; Programa Estadual de Vigilância de Epizootia, Secretaria de saúde de Rio Grande do Norte, Natal, Brazil., Arruda MF; Setor de Psicobiologia, Departamento de Fisiología Universidade Federal do Río Grande do Norte, Natal, Brazil., Peterson AT; Biodiversity Institute, University of Kansas, Lawrence, Kansas, United States of America., Megid J; Departamento Higiene Veterinária e Saúde Pública, Faculdade de Medicina Veterinária e Zootecnia, Universidade Estadual Júlio de Mesquita Filho, Botucatu, Brazil., Carrieri ML; Instituto Butantan, São Paulo, Brazil., Kotait I; Retired Researcher, Instituto Biológico, São Paulo, Brazil.
Jazyk: angličtina
Zdroj: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2022 Mar 31; Vol. 16 (3), pp. e0010254. Date of Electronic Publication: 2022 Mar 31 (Print Publication: 2022).
DOI: 10.1371/journal.pntd.0010254
Abstrakt: Rabies transmitted by wildlife is now the main source of human rabies in the Americas. The common marmoset, Callithrix jacchus, is considered a reservoir of rabies causing sporadic and unpredictable human deaths in Brazil, but the extent of the spillover risk to humans remains unknown. In this study, we described the spatiotemporal dynamics of rabies affecting C. jacchus reported to Brazil's Ministry of Health passive surveillance system between 2008 and 2020, and combined ecological niche modelling with C. jacchus occurrence data to predict its suitable habitat. Our results show that 67 outbreaks (91 cases) of rabies affecting C. jacchus were reported by 41 municipalities between January 2008 and October 2020, with a mean of 5 outbreaks/year [range: 1-14]. The maximum number of outbreaks and municipalities reporting cases occurred in 2018, coinciding with higher surveillance of primate deaths due to Yellow Fever. A mean of 3 [1-9] new municipalities reported outbreaks yearly, suggesting potential spatial expansions of the C. jacchus variant in northeastern Brazil and emerging rabies spillover from vampire bat Desmodus rotundus to C. jacchus in the north and south. Outbreaks were concentrated in the states of Ceará (72%) and Pernambuco (16%) up to 2012, but are now reported in Piauí since 2013, in Bahia since 2017 (D. rotundus' antigenic variant, AgV3) and in Rio de Janeiro since 2019 (AgV3). Besides confirming suitable habitat for this primate in the northeast and the east coast of Brazil, our Maximum Entropy model also predicted suitable habitat on the north and the west states of the country but predicted low habitat suitability among inland municipalities of the Caatinga biome reporting rabies. Our findings revealed new areas reporting rabies infecting C. jacchus, highlighting the need to implement strategies limiting spillover to humans and to better understand the drivers of C. jacchus rabies dynamics.
Competing Interests: The authors have declared that no competing interests exist. Ivanete Kotait was unable to confirm their authorship contributions. On their behalf, the corresponding author has reported their contributions to the best of their knowledge.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje