Birthweight z-score and fat-free mass at birth predict body composition at 3 years in Danish children born from obese mothers.
Autor: | Berglund NR; Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Frederiksberg, Denmark., Lewis JI; Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Frederiksberg, Denmark., Michaelsen KF; Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Frederiksberg, Denmark., Mølgaard C; Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Frederiksberg, Denmark., Renault KM; Department of Obstetrics and Gynecology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Carlsen EM; Department of Pediatrics, Hvidovre Hospital, Copenhagen University Hospital, Hvidovre, Denmark. |
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Jazyk: | angličtina |
Zdroj: | Acta paediatrica (Oslo, Norway : 1992) [Acta Paediatr] 2022 Jul; Vol. 111 (7), pp. 1427-1434. Date of Electronic Publication: 2022 Apr 05. |
DOI: | 10.1111/apa.16346 |
Abstrakt: | Aim: We investigated associations between newborn body composition and anthropometry and body composition at 3 years in Danish children born from obese mothers. Methods: Analyses are based on data from the observational cohort study SKOT II (SKOT; small children's diet and well-being (Danish)). Body composition at birth and at 3 years was assessed by dual-energy X-ray absorptiometry (DXA) scans and bioelectrical impedance analysis (BIA), respectively. Multiple linear regression models were applied to determine associations between newborn body composition and anthropometry and body composition at 3 years. Results: Birthweight z-score (BWZ) was positively associated with fat-free mass (FFM), height, fat-free mass index (FFMI), fat mass (FM) and fat mass index (FMI) at 3 years. Newborn FFM was positively associated with FFM, height, FFMI and FM at 3 years, and positive trends were seen between newborn FM and FM and FMI at 3 years. Conclusion: We showed that infants born with a higher BWZ go on to be taller at 3 years. They also grow to be heavier, to which FM and FFM both contribute, independently of linear growth. Additionally, it seems that FFM tracks into early childhood, thus supporting intrauterine programming of later health. (© 2022 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.) |
Databáze: | MEDLINE |
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