The Arched Rainbow Brow in Thyroid Eye Disease.

Autor:	Tran AQ; Department of Oculoplastic and Orbital Surgery, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, New York, U.S.A.; Department of Ophthalmology, University of Illinois Eye and Ear Infirmary, Chicago, Illinois, U.S.A., Yang C; Department of Ophthalmology, The Ohio State University, Columbus, Ohio, U.S.A., Tooley AA; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, U.S.A., Mahan M; Department of Ophthalmology, MedStar Georgetown/Washington Hospital Center, Washington, District of Columbia, U.S.A., Jamerson EC; Department of Oculoplastic and Orbital Surgery, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, New York, U.S.A., Kazim M; Department of Oculoplastic and Orbital Surgery, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, New York, U.S.A., Dagi Glass LR; Department of Oculoplastic and Orbital Surgery, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, New York, U.S.A.
Jazyk:	angličtina
Zdroj:	Ophthalmic plastic and reconstructive surgery [Ophthalmic Plast Reconstr Surg] 2022 Sep-Oct 01; Vol. 38 (5), pp. 469-474. Date of Electronic Publication: 2022 Mar 30.
DOI:	10.1097/IOP.0000000000002168
Abstrakt:	Purpose: To morphologically describe and mathematically quantify a novel clinical feature of thyroid eye disease (TED). Methods: A retrospective study was conducted of TED patients and age-sex-matched normal controls. The arched Rainbow Brow appearance in TED patients was determined by unanimous agreement of 3 oculoplastic surgeons. Eyebrow curvature was assessed by plotting 15 points along the eyebrow in ImageJ. The fourth-degree polynomial ( y = ax4 + bx3 + cx2 + dx + e ) was fitted to each eyebrow. Results: Two hundred seventy-one eyes were analyzed (200 TED and 71 age-sex-matched normal controls). A Rainbow Brow was identified in 42% of TED patients. A unilateral Rainbow Brow was seen in 15% of patients. The fourth-degree polynomial coefficients yielded significant differences between Rainbow Brow patients and age-sex-matched normal controls for the coefficients a, b, c , and d . Similar analysis of TED patients with and without a Rainbow Brow showed differences in coefficients a and b . Age >50 years ( p = 0.009) and the presence of brow fat expansion ( p < 0.001) were associated with the presence of a Rainbow Brow. Proptosis >24 mm showed a trend toward association with the presence of a Rainbow Brow ( p = 0.057). When considering the contribution of these features in a multivariable analysis, only brow fat expansion was a significant contributing factor ( p = 0.009). Conclusions: The Rainbow Brow is a distinct entity in TED and is likely consequent to brow fat pad expansion. Patients with a Rainbow Brow have different eyebrow curvature as compared to both normal age-sex-matched controls and TED patients without a Rainbow Brow. Competing Interests: The authors have no financial or conflicts of interest to disclose. (Copyright © 2022 The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc.)
Databáze:	MEDLINE
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