Feasibility of the wingate anaerobic exercise test as a clinical measure in patients with juvenile dermatomyositis.

Autor: Dover S; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Stephens S; Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON, Canada., Clairman H; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Abesamis A; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Jazi OA; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Babij S; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Marcuz JA; Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Rehabilitation, The Hospital for Sick Children, Toronto, ON, Canada., Naraidoo N; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Pan J; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Pullenayegum E; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada.; Institute of Health Policy, Management & Evaluation,, The Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada., Rumsey D; Division of Rheumatology, University of Alberta, Edmonton, AB, Canada., Whitney K; Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON, Canada.; Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada., Feldman BM; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada. brian.feldman@sickkids.ca.; Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON, Canada. brian.feldman@sickkids.ca.; Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada. brian.feldman@sickkids.ca.; Institute of Health Policy, Management & Evaluation,, The Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada. brian.feldman@sickkids.ca.
Jazyk: angličtina
Zdroj: Pediatric rheumatology online journal [Pediatr Rheumatol Online J] 2022 Mar 28; Vol. 20 (1), pp. 21. Date of Electronic Publication: 2022 Mar 28.
DOI: 10.1186/s12969-022-00679-6
Abstrakt: Background: Core sets, while widely adopted for clinical assessment in juvenile dermatomyositis (JDM), have some drawbacks - they are time consuming, were developed primarily for research, and require an experienced multidisciplinary team. We propose the Wingate Anaerobic Test, a 30-s all out test performed on a cycle ergometer, as a potential alternative; it is valid and reliable in this patient population. We aimed to determine the feasibility of performing the Wingate test as part of a typical clinic visit, and to determine if it is correlated to current measures of disease activity.
Methods: Patients 5-18 years of age, with JDM, were recruited from the JDM clinic at a large Canadian academic children's hospital. Participants underwent a standard clinic assessment, then completed a Wingate test at the end of the visit.
Results: Twenty-six patients participated in the study, representing a recruitment rate of 81%; of those, 88% were able to complete the Wingate test. Patients liked the Wingate test and felt it should be included as a regular clinic test. Absolute peak power (watts) on the Wingate test was strongly correlated to the manual muscle test (MMT-8) and the timed squat test. Relative peak power (watts/kg) on the Wingate test was strongly correlated to the timed squat test and the Childhood Myositis Assessment Scale (CMAS). Exploratory principal components analysis revealed that Wingate relative average power explained almost 2/3 of the variance of the CMAS, MMT and timed squats combined.
Conclusion: The Wingate test is a feasible test for children with JDM and correlates well with standard clinical assessments. Given its brevity, it has the potential to replace more standard measures of physical function currently used in clinical assessments for children with JDM. Future work should focus on how best to operationalize Wingate testing in clinic without the use of dedicated personnel.
(© 2022. The Author(s).)
Databáze: MEDLINE
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