Eruptive facial lentiginosis-like repigmentation in a patient with longstanding generalized vitiligo without a detectable trigger.

Autor: Kaiser D; Department of Dermatology, Ljubljana University Medical Centre, Ljubljana, Slovenia., Hosta V; Department of Dermatology, Ljubljana University Medical Centre, Ljubljana, Slovenia., Loubser J; St. George's University, St. George's, Grenada., Pavlović MD; Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Jazyk: angličtina
Zdroj: Acta dermatovenerologica Alpina, Pannonica, et Adriatica [Acta Dermatovenerol Alp Pannonica Adriat] 2022 Mar; Vol. 31 (Suppl), pp. S25-S26.
Abstrakt: Spontaneous appearance of hyperpigmented macules on chronic vitiligo lesions is a very rare phenomenon, which is described as eruptive lentiginosis. We describe the case of a patient with chronic non-segmental generalized vitiligo who presented with a sudden onset of hyperpigmented macules on depigmented areas of the face. A biopsy showed pigmented basal keratinocytes in the interfollicular epidermis, and immunohisochemistry with anti-SOX10 antibodies showed nuclei of single melanocytes. This case shows that even long-standing depigmented vitiligo lesions may contain functional melanocytes or their precursors.
Databáze: MEDLINE