The wild grass Brachypodium distachyon as a developmental model system.
| Autor: | Raissig MT; Centre for Organismal Studies Heidelberg, Heidelberg University, Heidelberg, Germany; Institute of Plant Sciences, University of Bern, Bern, Switzerland. Electronic address: michael.raissig@ips.unibe.ch., Woods DP; Department of Plant Sciences, University of California, Davis, CA, United States; Howard Hughes Medical Institute, Chevy Chase, MD, United States. Electronic address: dpwoods@ucdavis.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Current topics in developmental biology [Curr Top Dev Biol] 2022; Vol. 147, pp. 33-71. Date of Electronic Publication: 2022 Mar 14. |
| DOI: | 10.1016/bs.ctdb.2021.12.012 |
| Abstrakt: | The arrival of cheap and high-throughput sequencing paired with efficient gene editing technologies allows us to use non-traditional model systems and mechanistically approach biological phenomena beyond what was conceivable just a decade ago. Venturing into different model systems enables us to explore for example clade-specific environmental responses to changing climates or the genetics and development of clade-specific organs, tissues and cell types. We-both early career researchers working with the wild grass model Brachypodium distachyon-want to use this review to (1) highlight why we think B. distachyon is a fantastic grass developmental model system, (2) summarize the tools and resources that have enabled discoveries made in B. distachyon, and (3) discuss a handful of developmental biology vignettes made possible by using B. distachyon as a model system. Finally, we want to conclude by (4) relating our personal stories with this emerging model system and (5) share what we think is important to consider before starting work with an emerging model system. (Copyright © 2022 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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