Microorganisms and Antibiotic Resistance of Bacterial Keratitis at a Rural County Hospital in Seville.
| Autor: | Lorente Pascua J; Unidad de Gestión Clínica de Oftalmología Hospital Universitario Nuestra señora de Valme (J.L.B., A.G.B.), Seville, Spain; Unidad de Gestión Clínica de Microbiología Hospital Universitario Nuestra señora de Valme (E.G.S.), Seville, Spain; and Fundación Pública Andaluza para la Gestión de la Investigación en Salud en Sevilla (C.V.A.G.), Sede Hospital Universitario Nuestra señora de Valme, Seville, Spain., García Bernal A, Garcia Sanchez E, Almeida González CV |
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| Jazyk: | angličtina |
| Zdroj: | Eye & contact lens [Eye Contact Lens] 2022 Jun 01; Vol. 48 (6), pp. 267-271. Date of Electronic Publication: 2022 Mar 24. |
| DOI: | 10.1097/ICL.0000000000000883 |
| Abstrakt: | Purpose: To review the incidence, resistance patterns, and management of bacterial keratitis during the past 4 years. Methods: We retrospectively reviewed the clinical records of microbiological isolates from patients with a clinical diagnosis of bacterial keratitis. Results: A total of 159 patients were analyzed, and 102 microorganisms were isolated from 129 cultures. In these cultures, 23.7% of the microorganisms were gram positive, 60.8% were gram negative, and 15.5% were fungi. Pseudomonas aeruginosa was the most common bacteria (9.2%), followed by Serratia marcescens (4.4%) and Staphylococcus aureus (4%). Resistance to fluoroquinolones and aminoglycosides was found to be 23.1% and 53.1% in gram-positive and 2.8% and 13.9% in gram-negative bacteria, respectively. Resistance to ceftazidime against gram-negative bacteria was 13.9%. No resistance to vancomycin was observed. Conclusions: A high resistance rate to aminoglycosides and fluoroquinolones was observed in gram-positive bacteria. We concluded that fluoroquinolones or aminoglycosides may not be suitable for initial monotherapy in patients with severe bacterial keratitis. Competing Interests: The authors have no funding or conflicts of interest to disclose. (Copyright © 2022 Contact Lens Association of Ophthalmologists.) |
| Databáze: | MEDLINE |
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