Complementary catalysis and analysis within solid state additively manufactured metal micro flow reactors.

Autor: Monaghan T; School of Mechanical, Electrical and Manufacturing Engineering, Loughborough University, Loughborough, UK., Harding MJ; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin, Ireland., Christie SDR; Department of Chemistry, Loughborough University, Loughborough, UK., Harris RA; School of Mechanical Engineering, University of Leeds, Leeds, UK., Friel RJ; School of Information Technology, Halmstad University, Halmstad, Sweden. ross.friel@hh.se.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2022 Mar 24; Vol. 12 (1), pp. 5121. Date of Electronic Publication: 2022 Mar 24.
DOI: 10.1038/s41598-022-09044-9
Abstrakt: Additive Manufacturing is transforming how researchers and industrialists look to design and manufacture chemical devices to meet their specific needs. In this work, we report the first example of a flow reactor formed via the solid-state metal sheet lamination technique, Ultrasonic Additive Manufacturing (UAM), with directly integrated catalytic sections and sensing elements. The UAM technology not only overcomes many of the current limitations associated with the additive manufacturing of chemical reactionware but it also significantly increases the functionality of such devices. A range of biologically important 1, 4-disubstituted 1, 2, 3-triazole compounds were successfully synthesised and optimised in-flow through a Cu mediated Huisgen 1, 3-dipolar cycloaddition using the UAM chemical device. By exploiting the unique properties of UAM and continuous flow processing, the device was able to catalyse the proceeding reactions whilst also providing real-time feedback for reaction monitoring and optimisation.
(© 2022. The Author(s).)
Databáze: MEDLINE
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