The Future of Adhesion Prophylaxis Trials in Abdominal Surgery: An Expert Global Consensus.

Autor: De Wilde RL; University Hospital for Gynecology, Carl von Ossietzky University, 26121 Oldenburg, Germany., Devassy R; Centre of Excellence in Gynecological Minimal Access Surgery and Oncology, Dubai London Clinic & Specialty Hospital, Dubai 3371500, United Arab Emirates., Broek RPGT; Department of Surgery, Radboud University Nijmegen, 6525 XZ Nijmegen, The Netherlands., Miller CE; The Advanced IVF Institute and the Advanced Gynecologic Surgery Institute, Park Ridge, IL 60068, USA., Adlan A; University of Malaya, Kuala Lumpur 50603, Malaysia., Aquino P; Quirino Memorial Hospital, Quezon City 1109, Philippines., Becker S; Department of Obstetrics and Gynecology, University Hospital Frankfurt, University of Malaya, 60590 Frankfurt, Germany., Darmawan F; Karmig Center, Gatot Soebroto Army Hospital, Jakarta 10410, Indonesia., Gergolet M; General Hospital Dr. Franc Derganc, 5290 Šempeter-Vrtojba, Slovenia., Habana MAE; College of Medicine and Philippine General Hospital, University of the Philippines, Manila 1000, Philippines., Khoo CK; Mount Elizabeth Novena Hospital, Singapore 329563, Singapore., Koninckx PR; Catholic University of Leuven, 3000 Leuven, Belgium., Korell M; Johanna Etienne Krankenhaus, 41462 Neuss, Germany., Krentel H; Bethesda Krankenhaus Duisburg, 47053 Duisburg, Germany., Musigavong O; Chaophya Abhaibhubejhr Hospital, Mueang Prachin Buri 25000, Prachin Buri, Thailand., Pistofidis G; Lefkos Stavros Hospital, 115 28 Athina, Greece., Puntambekar S; Galaxy Hospital, Pune 411004, India., Rachman IA; Army Central Hospital Gatot Soebroto, Jakarta 10410, Indonesia., Sendag F; Ege University, Izmir 35040, Turkey., Wallwiener M; Universitäts-Frauenklinik, 69120 Heidelberg, Germany., Torres-de la Roche LA; University Hospital for Gynecology, Carl von Ossietzky University, 26121 Oldenburg, Germany.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2022 Mar 08; Vol. 11 (6). Date of Electronic Publication: 2022 Mar 08.
DOI: 10.3390/jcm11061476
Abstrakt: Postoperative adhesions represent a frequent complication of abdominal surgery. Adhesions can result from infection, ischemia, and foreign body reaction, but commonly develop after any surgical procedure. The morbidity caused by adhesions affects quality of life and, therefore, it is paramount to continue to raise awareness and scientific recognition of the burden of adhesions in healthcare and clinical research. This 2021 Global Expert Consensus Group worked together to produce consented statements to guide future clinical research trials and advise regulatory authorities. It is critical to harmonize the expectations of research, to both develop and bring to market improved anti-adhesion therapies, with the ultimate, shared goal of improved patient outcomes.
Databáze: MEDLINE
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