Beneath the surface: a case report of metastatic iridociliary ring melanoma treated with pembrolizumab.
| Autor: | Parra-Bernal C; Ocular Oncology Service, Institute of Ophthalmology and Visual Sciences, Tecnologico de Monterrey, Monterrey, Mexico., Aguilera-Partida JA; Uveitis and Ocular Inflammation Service, Clínica Oftalmológica Santa Lucía, Guadalajara, Jalisco, Mexico., Dalvin LA; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Rodríguez-Reyes AA; Ophthalmic Pathology Service, Asociación Para Evitar La Ceguera en México, Hospital Dr. Luis Sanchez Bulnes, Mexico City Mexico., Ancona-Lezama D; Ocular Oncology Service, Institute of Ophthalmology and Visual Sciences, Tecnologico de Monterrey, Monterrey, Mexico. |
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| Jazyk: | angličtina |
| Zdroj: | Arquivos brasileiros de oftalmologia [Arq Bras Oftalmol] 2024 Jan 22; Vol. 86 (5), pp. e20230046. Date of Electronic Publication: 2024 Jan 22 (Print Publication: 2024). |
| DOI: | 10.5935/0004-2749.20230046 |
| Abstrakt: | Iridociliary ring melanoma is an uncommon type of uveal melanoma. Clinical manifestation varies from asymptomatic cases to masquerade syndromes mimicking refractory glaucoma. Treatment options include radiotherapy and enucleation. Management of metastatic uveal melanoma remains discouraging. Novel therapies using immune checkpoint inhibitors are currently under study. We present a case of a 54-year-old Hispanic woman with progressive vision loss due to metastatic ring melanoma with anterior chamber seeding treated with pembrolizumab. |
| Databáze: | MEDLINE |
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