Autistic traits and alcohol use in adolescents within the general population.

Autor: Pijnenburg LJ; GGZ Rivierduinen, Institute for Mental Health Care, Leiden, The Netherlands. l.j.pijnenburg@amsterdamumc.nl.; Department of Psychiatry, Academic Medical Center, University of Amsterdam, Meibergdreef 5, 1105 AZ, Amsterdam, The Netherlands. l.j.pijnenburg@amsterdamumc.nl., Kaplun A; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., de Haan L; Department of Psychiatry, Academic Medical Center, University of Amsterdam, Meibergdreef 5, 1105 AZ, Amsterdam, The Netherlands., Janecka M; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.; Seaver Autism Center for Research and Treatment, New York City, NY, USA., Smith L; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Reichenberg A; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.; Seaver Autism Center for Research and Treatment, New York City, NY, USA., Banaschewski T; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159, Mannheim, Germany., Bokde ALW; Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland., Quinlan EB; Medical Research Council - Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Desrivières S; Medical Research Council - Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Grigis A; NeuroSpin, CEA, Université Paris-Saclay, 91191, Gif-sur-Yvette, France., Garavan H; Department of Psychiatry, University of Vermont, Burlington, VT, 05405, USA.; Department of Psychology, University of Vermont, Burlington, VT, 05405, USA., Gowland P; Sir Peter Mansfield Imaging Centre School of Physics and Astronomy, University of Nottingham, University Park, NG, UK., Heinz A; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany., Ittermann B; Physikalisch-Technische Bundesanstalt (PTB), Braunschweig, Germany.; Physikalisch-Technische Bundesanstalt (PTB), Berlin, Germany., Martinot JL; Maison de Solenn, Paris, France.; Institut National de la Santé et de la Recherche Médicale, INSERM Unit 1000 'Neuroimaging and Psychiatry', UniversityParis Sud, University Paris Descartes, Sorbonne Université, Paris, France., Martinot MP; Maison de Solenn, Paris, France.; Department of Child and Adolescent Psychiatry, AP-HP, Pitié-Salpêtrière Hospital, Paris, France., Nees F; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159, Mannheim, Germany.; Institute of Cognitive and Clinical Neuroscience, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Square J5, Mannheim, Germany., Orfanos DP; NeuroSpin, CEA, Université Paris-Saclay, 91191, Gif-sur-Yvette, France., Paus T; Department of Psychology, Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, University of Toronto, Toronto, ON, M6A 2E1, Canada.; Department of Psychiatry, Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, University of Toronto, Toronto, ON, M6A 2E1, Canada., Poustka L; Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Centre Göttingen, von-Siebold-Str. 5, 37075, Göttingen, Germany., Hohmann S; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159, Mannheim, Germany., Millenet S; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159, Mannheim, Germany., Fröhner JH; Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, Germany., Smolka MN; Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, Germany., Walter H; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany., Whelan R; School of Psychology and Global Brain Health Institute, Trinity College Dublin, Dublin, Ireland., Schumann G; Medical Research Council - Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; PONS Research Group, Department of Psychiatry and Psychotherapy, Humboldt University, Campus Charite Mitte, Berlin, Germany.; Institute for Science and Technology of Brain-Inspired Intelligence (ISTBI), Fudan University, Shanghai, People's Republic of China., Velthorst E; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.; Seaver Autism Center for Research and Treatment, New York City, NY, USA.
Jazyk: angličtina
Zdroj: European child & adolescent psychiatry [Eur Child Adolesc Psychiatry] 2023 Sep; Vol. 32 (9), pp. 1633-1642. Date of Electronic Publication: 2022 Mar 23.
DOI: 10.1007/s00787-022-01970-3
Abstrakt: It has been suggested that autistic traits are associated with less frequent alcohol use in adolescence. Our study seeks to examine the relationship between autistic traits and alcohol use in a large adolescent population. Leveraging data from the IMAGEN cohort, including 2045 14-year-old adolescents that were followed-up to age 18, we selected items on social preference/skills and rigidity from different questionnaires. We used linear regression models to (1) test the effect of the sum scores on the prevalence of alcohol use (AUDIT-C) over time, (2) explore the relationship between autistic traits and alcohol use patterns, and (3) explore the specific effect of each autistic trait on alcohol use. Higher scores on the selected items were associated with trajectories of less alcohol use from the ages between 14 and 18 (b = - 0.030; CI 95% = - 0.042, - 0.017; p < 0.001). Among adolescents who used alcohol, those who reported more autistic traits were also drinking less per occasion than their peers and were less likely to engage in binge drinking. We found significant associations between alcohol use and social preference (p < 0.001), nervousness for new situations (p = 0.001), and detail orientation (p < 0.001). Autistic traits (social impairment, detail orientation, and anxiety) may buffer against alcohol use in adolescence.
(© 2022. The Author(s).)
Databáze: MEDLINE
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