Cardiac involvement in cancer patients under chemotherapy and diagnosed with COVID-19: case report and literature review.

Autor: Mechal H; COVID-19 Dedicated Cardiology Team, University Hospital Center of Casablanca, Morocco., Benmalek R; COVID-19 Dedicated Cardiology Team, University Hospital Center of Casablanca, Morocco., Choukrallah H; COVID-19 Dedicated Cardiology Team, University Hospital Center of Casablanca, Morocco., Maaroufi A; COVID-19 Dedicated Cardiology Team, University Hospital Center of Casablanca, Morocco., Habbal R; COVID-19 Dedicated Cardiology Team, University Hospital Center of Casablanca, Morocco., Benouna EGM; COVID-19 Dedicated Cardiology Team, University Hospital Center of Casablanca, Morocco., Mounir A; COVID-19 Dedicated ICU Team, University Hospital Center of Casablanca, Morocco., Allali K; COVID-19 Dedicated ICU Team, University Hospital Center of Casablanca, Morocco., Cherkab R; COVID-19 Dedicated ICU Team, University Hospital Center of Casablanca, Morocco., Barrou L; COVID-19 Dedicated ICU Team, University Hospital Center of Casablanca, Morocco., Kettani CE; COVID-19 Dedicated ICU Team, University Hospital Center of Casablanca, Morocco.
Jazyk: angličtina
Zdroj: The Pan African medical journal [Pan Afr Med J] 2022 Jan 18; Vol. 41, pp. 45. Date of Electronic Publication: 2022 Jan 18 (Print Publication: 2022).
DOI: 10.11604/pamj.2022.41.45.23951
Abstrakt: Many cases of severe cardiac complications due to Coronavirus disease 2019 (COVID-19) were reported. Cancer and chemotherapy appear to be risk and prognostic factors for COVID-19. A 49-year-old Female, with a history of breast cancer treated by tumorectomy and anthracycline-based chemotherapy was admitted with acute respiratory distress syndrome (ARDS) confirmed as COVID-19. She also had elevated troponin I level (up to 43 g/L), and diffuse myocardial hypokinesia along with severe left ventricle dysfunction on echocardiography. Initial treatment included hydroxychloroquine, azithromycin, corticosteroids and mechanical ventilation. The evolution was marked by QT interval prolongation (QTc=523 ms) and occurrence of cardiogenic shock. The patient died of hemodynamic instability reluctant to resuscitation measures at the 2 nd day of hospitalization. COVID-19 patients may develop severe cardiac complications such as myocarditis and heart failure. Receiving chemotherapy especially anthracyclines may be a precipitating and prognostic factor of cardiac manifestations in COVID-19 cancer patients.
(Copyright: Hanane Mechal et al.)
Databáze: MEDLINE
Externí odkaz: