Hyperglycemia in pregnancy - prevalence and perinatal outcomes. A retrospective multicenter cohort study in Poland.

Autor:	Bomba-Opon DA; 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland. dorota.bomba-opon@wum.edu.pl., Godek B; 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland., Czekaj L; Bilnader Group, Gdansk, Poland., Huras H; Department of Obstetrics and Perinatology Jagielonian University, Cracow, Poland., Jakubiec-Wisniewska K; Department of Obstetrics and Perinatology Jagielonian University, Cracow, Poland., Janowiec K; Department of Obstetrics and Perinatology Jagielonian University, Cracow, Poland., Leszczynska-Gorzelak B; Department of Obstetrics and Perinatology, Medical University of Lublin, Poland., Slodzinska M; Department of Obstetrics and Perinatology, Medical University of Lublin, Poland., Zimmer M; 2nd Department of Obstetrics and Gynecology, Medical University of Wroclaw, Poland., Bek W; 2nd Department of Obstetrics and Gynecology, Medical University of Wroclaw, Poland., Rokita W; Department of Obstetrics and Gynecology, The Institute of Medical Sciences Jan Kochanowski University, Kielce, Poland., Zmelonek-Znamirowska A; Department of Obstetrics and Gynecology, The Institute of Medical Sciences Jan Kochanowski University, Kielce, Poland., Kalinka J; Department of Perinatology, Medical University of Lodz, Poland., Biesiada P; Department of Perinatology, Medical University of Lodz, Poland., Stanczyk P; Department of Perinatology, Medical University of Lodz, Poland., Cnota W; Department of Gynaecology and Obstetrics, Medical University of Silesia, Poland., Malec M; Department of Gynaecology and Obstetrics, Medical University of Silesia, Poland., Laudanski P; 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.; Department of Perinatology, Medical University of Bialystok, Poland., Zadykowicz R; Department of Perinatology, Medical University of Bialystok, Poland.; Department of Obstetrics, Perinatology and Gynecology, Medical University of Warsaw, Poland., Wielgos M; 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.
Jazyk:	angličtina
Zdroj:	Ginekologia polska [Ginekol Pol] 2022; Vol. 93 (12), pp. 1006-1012. Date of Electronic Publication: 2022 Mar 22.
DOI:	10.5603/GP.a2021.0257
Abstrakt:	Objectives: Hyperglycemia in pregnancy (HIP) is one of the most common complications of pregnancy. Recently adopted new criteria for the diagnosis of HIP as well as the greater prevalence of risk factors could have a significant impact on HIP prevalence. The objective of the study was to assess the rates of HIP and the associated complications. Material and Methods: This was a retrospective analysis of clinical records from pregnant women who delivered in eight tertiary hospitals in Poland in 2016. Results: The number of pregnant women with hyperglycemia totaled 1280 (7.25%), including gestational diabetes mellitus (GDM) in 1169 (6.62%) women and pregestational diabetes mellitus (PGDM) in 111 (0.63%). In addition to dietary modifications, 477 (41% of the GDM group) women received medical treatment (GDMG2). In women with PGDM multiple daily insulin injections (MDI) were used in 53 (47.7%) cases, continuous subcutaneous insulin infusions (CSII) in 57 (51.3%) cases and one woman was treated with metformin. The rate of cesarean sections was 69.4% and 62.9% for PGDM and GDM, respectively. Large-for-gestational-age (LGA) infants accounted for 38% and 21% of births in the PGDM and GDM groups, respectively. Of note are high rates of hyperbilirubinemia in infants born to mothers treated with insulin (13.5% for PGDM and 14.4% for GDMG2) vs infants born to mothers with diet (GDMG1) (3.4%). Conclusions: In Poland, the prevalence of HIP has nearly doubled in the past twenty years. Even with appropriate management, HIP is a significant risk factor for a cesarean section delivery, bearing an LGA infant and adverse neonatal outcomes.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu