Three new chromanes and one new flavone C -glycoside from Mallotus apelta .

Autor: Anh NH; Graduate University of Science and Technology, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Vietnam.; Faculty of Chemistry, Thai Nguyen University of Sciences, Thai Nguyen 24118, Vietnam., Yen DTH; Institute of Marine Biochemistry, VAST, Hanoi 10072, Vietnam., Cuong NT; Institute of Ecology and Biological Resources, VAST, Hanoi 10072, Vietnam., Tai BH; Graduate University of Science and Technology, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Vietnam.; Institute of Marine Biochemistry, VAST, Hanoi 10072, Vietnam., Yen PH; Graduate University of Science and Technology, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Vietnam., Chinh PT; Faculty of Chemistry, Thai Nguyen University of Sciences, Thai Nguyen 24118, Vietnam., Cuong PV; Institute of Marine Biochemistry, VAST, Hanoi 10072, Vietnam., Nam NH; Institute of Marine Biochemistry, VAST, Hanoi 10072, Vietnam., Kiem PV; Graduate University of Science and Technology, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Vietnam.; Institute of Marine Biochemistry, VAST, Hanoi 10072, Vietnam., Cho SH; Chuncheon Center, Korea Basic Science Institute, Gangwon-do 24341, Republic of Korea., Park S; Chuncheon Center, Korea Basic Science Institute, Gangwon-do 24341, Republic of Korea., Nhiem NX; Graduate University of Science and Technology, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Vietnam.; Institute of Marine Biochemistry, VAST, Hanoi 10072, Vietnam.
Jazyk: angličtina
Zdroj: Journal of Asian natural products research [J Asian Nat Prod Res] 2023 Jan; Vol. 25 (1), pp. 18-26. Date of Electronic Publication: 2022 Mar 20.
DOI: 10.1080/10286020.2022.2051494
Abstrakt: Three new chromanes, malloapeltas J-L ( 1 - 3 ), and one new flavone C -glycoside, malloflavoside ( 4 ), together with four known compounds, apigenin 6- C - β -D-xylopyranosyl-8- C - α -L-arabinopyranoside ( 5 ), apigenin 6- C - β -D-glucopyranosyl-8- C - α -L-arabinopyranoside ( 6 ), apigenin 7- O - β -D-apiofuranosyl-(1→2)- β -D-glucopyranoside ( 7 ), and acantrifoside E ( 8 ) were isolated from the methanol extract of the leaves of Mallotus apelta . Their chemical structures were determined using spectroscopic methods, including 1D, 2D NMR, and HR-ESI-MS methods. All the isolated compounds were evaluated their cytotoxic activity against human prostate cancer (PC-3) and human breast cancer (MCF-7) cells, but none of them showed cytotoxicities on both human cancer cell lines.
Databáze: MEDLINE
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