Prevalence of perinatal anxiety in low- and middle-income countries: A systematic review and meta-analysis.

Autor: Nielsen-Scott M; School of Medicine and Biomedical Sciences, University of Oxford, Oxford, UK., Fellmeth G; National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK. Electronic address: gracia.fellmeth@ndph.ox.ac.uk., Opondo C; National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Alderdice F; National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK; School of Nursing and Midwifery, Queen's University Belfast, Belfast, UK.
Jazyk: angličtina
Zdroj: Journal of affective disorders [J Affect Disord] 2022 Jun 01; Vol. 306, pp. 71-79. Date of Electronic Publication: 2022 Mar 16.
DOI: 10.1016/j.jad.2022.03.032
Abstrakt: Background: Perinatal anxiety is associated with adverse outcomes for women and their infants. Women in low- and middle-income countries (LMIC) may be at higher risk of perinatal anxiety. We aimed to systematically review and synthesise the evidence on prevalence of perinatal anxiety in LMIC.
Method: We searched MEDLINE, Embase, PscyhINFO, Global Health and Web of Science to identify studies assessing prevalence of perinatal anxiety in LMIC. Studies published since January 2016 were included. Screening and data extraction was conducted independently by two reviewers. Pooled prevalence estimates were calculated using random-effect meta-analyses and sources of heterogeneity explored through subgroup analyses and meta-regression.
Results: We screened 9494 titles and abstracts, reviewed 700 full-texts and included 54 studies in the systematic review and meta-analysis. The pooled prevalence of self-reported anxiety symptoms was 29.2% (95%CI 24.5-34.2; I 2 98.7%; 36 studies; n = 28,755) antenatally and 24.4% (95%CI 16.2-33.7; I 2 98.5%; 15 studies; n = 6370) postnatally. The prevalence of clinically-diagnosed anxiety disorder was 8.1% (95%CI 4.4-12.8; I 2 88.1% 5 studies; n = 1659) antenatally and 16.0% (95% CI 13.5-18.9; n = 113) postnatally.
Limitations: Our search was limited to studies published since January 2016 in order to update a previous review on this topic.
Conclusion: Perinatal anxiety represents a significant burden in LMIC, with one in four women experiencing symptoms during pregnancy or postpartum. Research remains lacking in a significant proportion of LMIC, particularly in the lowest income countries. Further research should guide application of screening tools in clinical settings to identify women with anxiety disorders in order to provide appropriate treatment.
(Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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