The effect of left ventricular longitudinal strain on left atrial function and ventricular filling in hypertension.

Autor: Erdei T; CMR Unit, Bristol Heart Institute, Bristol BS2 8HW, UK., Rodrigues JCL; CMR Unit, Bristol Heart Institute, Bristol BS2 8HW, UK; Clinical Radiology, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol BS2 8HW, UK; Cardionomics Research Group, University of Bristol, Bristol BS8 1TY, UK., Hartley-Davies R; Medical Physics, University Hospitals Bristol NHS Foundation Trust, Bristol BS2 8HW, UK., Dastidar AG; CMR Unit, Bristol Heart Institute, Bristol BS2 8HW, UK., Szantho GV; CMR Unit, Bristol Heart Institute, Bristol BS2 8HW, UK., Hart EC; Cardionomics Research Group, University of Bristol, Bristol BS8 1TY, UK., Nightingale AK; Cardionomics Research Group, University of Bristol, Bristol BS8 1TY, UK., Manghat NE; CMR Unit, Bristol Heart Institute, Bristol BS2 8HW, UK; Clinical Radiology, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol BS2 8HW, UK; Cardionomics Research Group, University of Bristol, Bristol BS8 1TY, UK., Hamilton MCK; CMR Unit, Bristol Heart Institute, Bristol BS2 8HW, UK; Clinical Radiology, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol BS2 8HW, UK. Electronic address: mark.hamilton@uhbw.nhs.uk.
Jazyk: angličtina
Zdroj: Clinical radiology [Clin Radiol] 2022 May; Vol. 77 (5), pp. e379-e386. Date of Electronic Publication: 2022 Mar 15.
DOI: 10.1016/j.crad.2022.01.056
Abstrakt: Aim: To assess the relationship of global longitudinal strain during left atrial (LA) and left ventricular (LV) filling and emptying.
Materials and Methods: Using magnetic resonance imaging in 47 hypertensive patients, biplane global LV longitudinal strain was evaluated and related to LA and LV filling and emptying (by volumetric analysis), and to pulmonary vein and trans-mitral flow (by phase-contrast imaging). The results were compared to normal subjects.
Results: In hypertensive patients, reduced global longitudinal LV strain was associated with reduced LA reservoir (47 ± 10 versus 53 ± 9%, p<0.05), reduced LA conduit function (21 ± 9 versus 32 ± 11%, p<0.004), reduced LA early peak emptying rate (150 ± 77 versus 230 ± 88 ml/s, p=0.007), and slower early LV filling (373 ± 141 versus 478 ± 141 ml/s, p=0.03). LA peak filling rate showed a positive correlation to LV peak emptying rate (R=0.331, p=0.02).
Conclusion: In hypertensive heart disease, impaired LV longitudinal systolic function causes reduced LA filling and emptying, and this leads directly to impaired LV filling and diastolic dysfunction.
(Crown Copyright © 2022. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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