Potential of engineering the myo-inositol oxidation pathway to increase stress resilience in plants.

Autor: Alok A; Department of Biotechnology, UIET, Punjab University, Chandigarh, India. anshualok2@gmail.com.; Department of Plant Pathology, University of Minnesota, Saint Paul, MN, 55108, USA. anshualok2@gmail.com., Singh S; International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Patancheru, India., Kumar P; School of Agricultural Biotechnology, Punjab Agricultural University, Ludhiana, India., Bhati KK; Louvain Institute of Biomolecular Sciences, Catholic University of Louvain, Louvain-la-Neuve, Belgium. Kaushal.bhati@uclouvain.be.
Jazyk: angličtina
Zdroj: Molecular biology reports [Mol Biol Rep] 2022 Aug; Vol. 49 (8), pp. 8025-8035. Date of Electronic Publication: 2022 Mar 16.
DOI: 10.1007/s11033-022-07333-0
Abstrakt: Myo-inositol is one of the most abundant form of inositol. The myo-inositol (MI) serves as substrate to diverse biosynthesis pathways and hence it is conserved across life forms. The biosynthesis of MI is well studied in animals. Beyond biosynthesis pathway, implications of MI pathway and enzymes hold potential implications in plant physiology and crop improvement. Myo-inositol oxygenase (MIOX) enzyme catabolize MI into D-glucuronic acid (D-GlcUA). The MIOX enzyme family is well studied across few plants. More recently, the MI associated pathway's crosstalk with other important biosynthesis and stress responsive pathways in plants has drawn attention. The overall outcome from different plant species studied so far are very suggestive that MI derivatives and associated pathways could open new directions to explore stress responsive novel metabolic networks. There are evidences for upregulation of MI metabolic pathway genes, specially MIOX under different stress condition. We also found MIOX genes getting differentially expressed according to developmental and stress signals in Arabidopsis and wheat. In this review we try to highlight the missing links and put forward a tailored view over myo-inositol oxidation pathway and MIOX proteins.
(© 2022. The Author(s), under exclusive licence to Springer Nature B.V.)
Databáze: MEDLINE
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